GLUT transporters

The GLUT transporters, such as GLUT1 of erythrocytes, carry glucose into cells by facilitated diffusion. These transporters are uniporters, carrying only one substrate. Symporters permit simultaneous passage of two... 

It is generally believed that GLUT transporters are symmetric [61], so they can transport both ways with the same affinity. Thus, the efflux is given by ... 

GLUT Transporters Compare the localization of GLUT4 with that of GLUT2 and GLUT3, and explain why these localizations are important in the response of muscle, adipose tissue, brain, and liver to insulin. 

Fructose is not co-transported with sodium it enters the cell on a GLUTS transporter. Glucose, galactose and fructose are transported out of the enterocyte through the GLUT2 transporter in the basolateral membrane. 

Genetic techniques have identified additional GLUT transporters (GLUT 7-12), but the role of these transporters has not yet been fully described. 

Glucose transport across membranes occurs via a transporter protein, i.e. GLUT transporters. These transmembrane proteins bind glucose on one face of the membrane, then undergo conformational change to translocate glucose across the membrane. The different types of GLUT transporter are oudined in the table... 

Gene activated Lipoprotein lipase fatty acid transporter protein adipocyte fatty acid binding protein acyl-CoA synthetase malic enzyme GLUT-4 glucose transporter phosphoenolpyruvate carboxykinase... 

In addition to secretory cells, many non-secretory cells are capable of regulating exocytotic fusion of transport vesicles that are derived from endosomal precursors. For instance, vesicles enriched in plasma membrane transport proteins are incorporated in a regulated manner in order to alter metabolite fluxes. Examples include the glucose transporter GLUT-4 in muscle and fat tissues, a key element in the control of... 

Glucose transport activity is regulated through transcriptional and translational control of the GLUT proteins, through their activity, and through alterations of their intracellular distribution. Most importantly, the GLUT4 continuously cycles between an intracellular,... 

Joost H-G, Thorens B (2001) The extended GLUT-family of sugar/polyol transport facilitators - nomenclature, sequence characteristics, and potential function of its novel members. Mol MembrBiol 18 247-256... 

Scheepers A, Joost HG, Schurmann A (2004) The glucose transporter families SGLT and GLUT molecular basis of normal and aberrant function. JPEN J Parenter Enteral Nub 28 364-371... 

Wood IS, Trayhurn P (2003) Glucose transporters (GLUT and SGLT) expanded families of sugar transport proteins. BrJNutr 89 3-9... 

GLUT stands for Glucose Transport Facilitators. Glucose Transporters... 

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