Glucose transporter Glut

In addition to secretory cells, many non-secretory cells are capable of regulating exocytotic fusion of transport vesicles that are derived from endosomal precursors. For instance, vesicles enriched in plasma membrane transport proteins are incorporated in a regulated manner in order to alter metabolite fluxes. Examples include the glucose transporter GLUT-4 in muscle and fat tissues, a key element in the control of... 

Wood IS, Trayhurn P (2003) Glucose transporters (GLUT and SGLT) expanded families of sugar transport proteins. BrJNutr 89 3-9... 

Doege, H., et al. Characterization of human glucose transporter (GLUT) 11 (encoded by SLC2A11), a novel sugar-transport facilitator specifically expressed in heart and skeletal muscle. Biochem. J. 2001, 359, 443-449. 

Glucose entry into most cells is concentration driven and independent of sodium. Four glucose transporters (GLUT) are listed in Table 1-12-1. They have different afiinities for glucose coinciding with their respective physiologic roles. Normal glucose concentration in peripheral blood is 4-8 mM (70-140 m dL). 

Airley R, Loncaster J, Davidson S et al (2001) Glucose transporter glut-1 expression correlates with tumor hypoxia and predicts metastasis-free survival in advanced carcinoma of the cervix. Clin Cancer Res 7 928-934... 

Zeng, C.-M., Zhang, Y, Lu, L., Brekkan, E., Lundqvist, A., and Lundahl, R, Immobilization of human red cells in gel particles for chromatographic activity studies of the glucose transporter Glut 1, Biochim. Biophys. Acta, 1325, 91-98, 1997. 

Expression, Regulation, and Functional Role of Glucose Transporters (GLUTs) in Brain... 

One of the most successful radiopharmaceuticals in oncology (and in other fields of noninvasive diagnostic medicine) is certainly lsF-labeled glucose, 2-lsF-2-deoxy-glucose, so-called FDG [60]. FDG is taken up by the glucose transporters GLUT,... 

Dehydroascorbate enters cells byway of the (insulin-dependent) glucose transporters (GLUT), and is reduced to ascorbate intracellularly. 

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