Glove port

Fig. 2.9. Glove ports, (a) A conventional glove port. (6) Glove port with cover to allow evacuation. (Adapted from USAEC Report TID-16020, N. Garden, Ed., 1962.)...

When a new glove box is being designed or an old one modified, the glove ports should be positioned to provide access to the entire bottom of the box and... 

It is easily understood that if the aseptic operation is performed in a separated small space from which personnel have been completely excluded, the necessity for room classification based on particulate and environmental microbiological monitoring requirements may be significantly reduced. In other words, critical operations in an aseptic area should be performed in the smallest space, and intervention by personnel should be minimized by indirect means through the use of protective glove ports and/or half suits. Application of these methods can minimize the chance of contamination. Following are such systems currently in place to reduce the contamination rate in aseptic processing. 

In the context of aseptic processing systems, a barrier is a device that restricts contact between operators and the aseptic field enclosed within the barrier. Barriers may not be sterilized and do not always have transfer systems that allow the passage of materials into or out of the system without exposure to the surrounding environment. Barriers range from plastic curtains around the critical production zones to rigid enclosures found on modern aseptic-filling equipment. Barriers may also incorporate such elements as glove ports, half suits, and rapid-transfer ports. 

Figure 17.3 Isolator with multiple glove ports in different sizes.

Equipment Accessibility. Care should be taken to minimize the amount of bending or stretching that operators need to perform. Equipment should be placed directly in front of and centered between two glove ports if possible. 

Solids discharge manually using glove ports... 

III BSC is used where absolute containment of hazardous agents is required, and is normally configured with glove ports housing gas-tight, full length latex, neoprene, PVC, urethane, or laminated polymer glovesJ ... 

Bart et al. (62) have described the enclosure of a Mettler TA-1 thermoanalyzer in a sealed system in order to permit the examination of samples containing alpha and beta/gamma emissions. Samples containing plutonium and uranium may be studied by TG with no radiation hazard to the operator. All balance components could be reached through glove ports. 

Except for the electronic componentsr the electrophoretic apparatus was housed in a constant-temperature chamberr held at 37 C 1 with glove ports and windows through which the eyepieces of... 

Whereas most special growth chambers in use are by necessity not sealed and are closely linked to the outside environment to permit easy control of temperature and humidity, and in many cases for a continuous supply of carbon dioxide, the growth chambers discussed here were designed with the same philosophy used where manipulation of radioactive or other toxic materials must be employed. Our growth chambers thus are provided with glove ports for internal manipulations, hermeticdly sealed bulkheads, etc. 

Figure 9.4 Class I safety cabinet. Top, diagram showing air flow directions for left, open front center and right, glove port front. Bottom, photograph of a Class I cabinet. (Photograph courtesy of the Baker Co.)...

Recently, there has been increased use of vaporized hydrogen peroxide in the validation and bio-decontamination of half-suit and glove-port isolators in pharmaceutical production. 

---