Glioblastoma multiforme tissue

The IR spectra (traces A-C) in Figure 3.2 demonstrate the effect of treating tissue sechons with polar and nonpolar solvents. The IR spectrum (trace A) was obtained from a dried tissue section of a glioblastoma multiforme (GBM) brain tumor. Compared to the spectra in Figure 3.1, it is evident that this hssue is mainly composed of proteins and lipids. The IR spectrum (trace B) was acquired from a consecuhve hssue sechon that had been treated for 10 min with a drop of toluol. The overlay of the normalized spectra indicates that Upid-assodated bands at 1740,... 

Figure 3.7 (a-k) FT-IR images often brain tissue sections obtained from a brain tumor patient with a multifocal glioblastoma multiforme. The color code represents the classification by a LDA model into six classes regular (green), low increased (blue),... 

Glial tissue "Benign" gliomas Glioblastoma multiforme, astrocytoma... 

Tsurushima H, Liu SQ, Tsuboi K, Yoshii Y, Nose T, Ohno T. Induction of human autologous cytotoxic T lymphocytes against minced tissues of glioblastoma multiforme. J Neurosurg 1996 84 258-263. 

BNCT has been extensively studied as a possible therapy in the treatment of brain tumors, specifically glioblastoma multiforme (GBM). This is one of the most malignant forms of cancer that constitutes about 60,000 cases per year. It is invariably fatal with a mean survival time of 18 months from diagnosis. This cancer infiltrates the brain so aggressively that surgery is rarely able to remove all the cancerous tissue it must be considered a whole brain disease. ° On the positive side, these types of tumors have little history of metastasizing to other organ sites in the body. Thus, if... 

Brain tissue and tumors have rarely been studied using FTIR, although Salzer et al (23) have recently described the use of FTIR mapping as a basis for the classification of human astrocytic gliomas. Glioblastoma multiforme (GBM) is a highly malignant human brain tumor and numerous clinical studies and... 

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