Ginseng abuse syndrome

Siegel RK. Ginseng abuse syndrome problems with the panacea. JAMA 241 (15) 1614-1615, 1979. 

Siegel RK. (1979). Ginseng abuse syndrome. Problems with the panacea. JAMA. 241(15) 1614-15. Simon MF, Chap H, Braquet P, Douste-Blazy L. (1987). Effect of BN 52021, a specific antagonist of platelet activating factor (PAF-acether), on calcium movements and phosphatidic acid production induced by PAF-acether in human platelets. Thromb Res. 45(4) 299-309. 

On the other hand, a number of adverse event reports recorded in the literature are themselves erroneous in nature due to the quality of the assessment and reporting, with Siegel s report of the so-called ginseng-abuse-syndrome (GAS) being a prime example (24). In this report, the author simply recorded adverse reactions in patients who had ingested ginseng without reference to which of a number of plants having the same common... 

Siegel R. Ginseng abuse syndrome. Problems with the panacea. JAMA 1979 241 1614-1615. 

Siegel, R. 1979. Ginseng abuse syndrome Problems with the panacea. JAMA 241, 1614-1615. Siegers, C. 1992. Anthranoid laxatives and colorectal cancer. Trends Pharmacol. Sci. 13, 229-231. Simpson, E., Law, S., and Storrs, F. 2004. Prevalence of botanical extract allergy in patients with contact dermatitis. Dermatitis 15, 67-72. 

Use of eleuthero was reported in association with "ginseng abuse syndrome" (see Panax ginseng entry) (Siegel 1979). The study that included this information has been criticized for methodological flaws, notably, that no distinction... 

Blumenthal, M. 1991. Debunking the ginseng abuse syndrome. INhole Foods (Mar.) 89-91. 

Haemolytic activities of Ginseng saponins have been reported 194, 195) and cytotoxic activities of dammarane type triterpenes have been investigated 196). Of interest also is a Ginseng abuse syndrome 197) which was commented upon at the third International Ginseng Symposium in Seoul, Korea. 

Siegel, R. K. Ginseng Abuse Syndrome, Problems with the Panacea. JAMA 241, 1614... 

We are currently being literally choked by an overabundance of data on natural products, much of which either has not been evaluated or is of dubious value. In this second edition, as in the first edition, every effort has been made to evaluate all original publications available to assure that the research methods and findings are of decent quality. And I have paid particular attention to the identity and quality control of the test materials. Papers reporting on results of studies based on unidentified or unidentifiable test materials are not cited under the respective entries (e.g., the so-called ginseng abuse syndrome not cited under ginseng) for the same reason that results of research on an unidentified yellow powder ... 

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