Germane Subject

The majority of allelic variants identified for CYP3 A4 and 3 A5 either have no phenotypic effect or result in diminished catalytic activity, which can result in an increase in circulating drug levels to some extent. A rare allelic form of CYP3A4 recently discovered in a German subject with a midazolam clearance of 2.99 mL (min kg)-1 has been shown to be due to the lack of heme incorporation into the heterologously expressed protein [192], The frequency of this variant in the general population has... 

Other than Mendeleev s Principles, the chemistry textbook of Victor von Richter (1841-91), another German subject of the Russian Empire, played an important role in the early promulgation of the periodic system both in Russia and in Germany. 

German subjects of the Russian Empire played an important role in promulgating the periodic system both inside and outside of Russia. This German mediation was another important factor for the acceptance of the periodic system. Victor von Richter, for example, conveyed new developments of the Russian chemical community to Germany as a correspondent for the German Chemical Society. He wrote extremely popular chemistry textbooks, one of the first ones based on the periodic system. His books both in Russian and German were not only published in many editions, but also translated into major European languages. 

There are extensive publications on many individual problems together with practical instmctions. However, it was difficult for the technologist in Germany to master the subject because no comprehensive up-to-date publication was available in German. The Subcommittee for Corrosion of DVGW instigated the publication of a handbook of cathodic protection, and a number of members offered their cooperation as authors of individual chapters. 

The use of the Hammett equation has also been extended to several new types of applications. Since these are not germane to the subject matter of the present chapter, we wiU simply mention work on applications to ethylenic and acetylenic compounds the various applications to physical properties, such as infrared frequencies and intensities, ultraviolet spectra, polarographic half-wave potentials, dipole moments,NMR and NQR spectra,and solubility data and applications to preparative data and biological activity. 

Persistent practice is the great essential to acquiring a foreign language vocabulary and sensing its word order and idioms. At the outset the chemical student will find it very helpful to read in German elementary chemical textbooks with the subject matter of which he is familiar. This will serve the double purpose of review and German practice. 

Reliance on forcing consumers to subsidize is hardly unique to German coal. U.S. public utility regulation long has required unequal pricing among consumers. Historically, emphasis was on rates that caused industrial and commercial users to subsidize residential users. This has encouraged industrial customers to secure rate reforms. These are equity measures that are subject to the criticisms stated above. 

Fundamental research in pyrotechnics is published in the US in Combustion and Flame by the Combustion Institute, and in the UK in Combustion Science and Technology and in Fuel . Germany has the new, journal, Propellants and Explosives (German Chemical Society), which is the successor to the discontinued Explosivstoffe . A necessary caveat is that these journals are strongly oriented toward combustion or propulsion so that only rarely do they yield pyrotechnic information. Likewise, the various publications of the learned societies contain much data on thermodynamics, spectroscopy, and instrumental analysis which are useful in the study of pyrotechnics. In the USSR the situation is somewhat better as Physics of Combustion and Explosion (Fizika Gorenia i Vzryva) of the Siberian Branch Academy of Sciences USSR is exclusively oriented toward subjects of interest, as several scientific institutes are primarily devoted to research in pyrotechnics. The same authors do publish also, however, in the journals of the Academy of Science USSR (of which there are several) as well as in the corresponding journals of the academies of the various republics, so that the impression is created of a high level of activity... 

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