Genetics review

Proteins Structure, Function, and Genetics Reviews in Modern Physics... 

Oda Y, Tsuneyoshi M. Extrarenal rhabdoid tumors of soft tissue Clinicopathological and molecular genetic review and distinction from other soft-tissue sarcomas with rhabdoid features. Pathol Int. 2006 56 287-295. 

Judson R 1997, Genetic Algorithms and Their Use in Chemistry. In Lipkowitz K B and D B Boyd (Editors) Reviews in Computational Chemistry Volume 10. New York, VCH Publishers, pp. 1-73. 

A Chinese pubHcation (47) with 17 references reviews the use of genetically engineered microorganisms for the production of L-ascorbic acid and its precursor, 2-KGA (49). For example, a 2-keto-L-gulonic acid fermentation process from sorbose has been pubUshed with reported yields over 80% (50). 

Bacitracin. Bacitracin, a cycHc peptide active against gram-positive bacteria, was discovered in 1943. Bacitracin received dmg certification in 1949 (60—62). Whereas human usage of bacitracin is almost exclusively topical, the vast majority of bacitracin manufactured worldwide is used as an animal feed additive. Reviews of work on bacitracin include its chemistry (63—67), comprehensive aspects (62), medical aspects (62,68), biosynthesis on large enzyme complexes and genetics (69—71), and production (71,72). 

Finally, the synthesis of biodegradable poly(hydroxyalkanoic acids) (PHA) by bacteria or genetically modified plants should be mentioned. The microbiology, biochemistry, and genetics of PHA biosynthesis have been reviewed by several authors52,105,405 407 and are beyond the scope of this chapter. 

The Competent Authorities are allowed a maximum of 60 days to review the data, or 90 days in the case of trials involving medicinal products for gene therapy, somatic cell therapy (including xenogeneic cell therapy), and all medicinal products containing genetically modified organisms. Such trials require written authorisation from the Competent Authority as distinct from other types of product where the authorities may just notify the sponsor of the acceptability (no-objection) of the application. If issues are raised, the sponsor may amend the application once, with a consequent extension to the allowed review period. 

Ebringerova A, HromddkovdZ (1999) In Harding SE (ed) Biotechnology and Genetic Engineering Reviews. Intercept, England, vol. 16, p. 325... 

Freeling, M. Bennett, D.C. (1985). Maize Adhl. Annual Review of Genetics, 19, 297-323. 

EM Southern, K Mir, M Shchepinov. Nat. Genet. 21 5-9, 1999 see also the series of review articles published in this supplement of Nat. Genet. 

Annual Reviews of Biochemistry, Cell and Developmental Biology, Genetics, Genomics and Human... 

---