General Compatibility

Abdul S, Poddar SS. A flexible technology for modified release of drugs multi-layered tablets. J Control Release 2004, 7 Jul 97(3) 393-405. 

Abrams J. Glyceryl trinitrate (nitroglycerin) and the organic nitrates. Choosing the method of administration. Drugs 1987 Sep 34(3) 391-403. 

Aldridge MA, Ito MK. Colesevelam hydrochloride a novel bile acid-binding resin. Ann Pharmacother 2001 Jul-Aug 35(7-8) 898-907. 

Atkins PJ. Dry powder inhalers an overview. Respir Care 2005 Oct 50(10) 1304-1312 discussion 1312. 

Bach M, Lippold BC. Percutaneous penetration enhancement and its quantification. Eur J Pharm Biopharm 1998 Jul 46(1) 1-13. 

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PVF resins are generally compatible with phthalate, phosphate, adipate, and diben2oate plastici2ers, and with phenoHc, melamine—formaldehyde, urea—formaldehyde, unsaturated polyester, epoxy, polyurethane, and cellulose acetate butylate resins. They are incompatible with polyamide, ethyl cellulose, and poly(vinyl chloride) resins (141). 

HEC is generally compatible with other ceUulosic water-soluble polymers to give clear, homogeneous solutions. When mixed with an anionic polymer such as CMC, however, interactions between the two polymers may result in synergistic behavior, ie, viscosities higher than predicted and calculated. HEC has excellent compatibiUty with natural gums. 

The use of allyl ethers for the protection of alcohols is common in carbohydrate literature because allyl ethers are generally compatible with the various methods... 

Our studies of the absorption, permeation, and extraction properties of containers produced from high nitrile barrier resins have demonstrated that they meet or surpass the basic criteria established for retention of taste and odor characteristics of carbonated soft drinks. Sensory tests, which can isolate and identify end results as well as integrate collective effects, have confirmed this judgement and have established the general compatibility of these containers with a variety of beverage products from a taste and odor standpoint. Furthermore, these materials have the excellent physical properties required for containers which will find wide use in food and beverage packaging. 

The ethylene pressures used were 0.5, 1, and 2 millitorr. Thus, the slopes of the three lines should be in the ratios 2 1 0.5. The lines in Figure 6 were drawn to give a best fit of the experimental points and comply with the above condition. The considerable scatter in the experimental points is possibly caused by inexact concentration ratios in the reaction mixture. In spite of some curvature, most noticeable for the 0.5-millitorr results, the experimental results are generally compatible with Equation II since they follow the required slope ratios, have a common intersection with the ordinate, and show approximate linearity with the square of the pressure. 

Anionic and cationic products generally tend to interact with each other, usually diminishing the surface-active properties of both and often resulting in precipitation of the complex formed. Amphoteric compounds can also be incompatible with anionics in acid solution but are generally compatible with cationics and nonionics. Interaction between anionic and cationic agents can sometimes be prevented by addition of a nonionic. In some cases, if an ethoxylated sulphate or phosphate is used as the anionic component a cationic compound produces no obvious precipitation, since the oxyethylene chain acts as dispersant for any complex that may be formed. 

Crystallographers have traditionally travelled to synchrotrons for data collection. However, this approach is not generally compatible with high-throughput data collection. For example, significant time is often expended merely in transporting technical staff to the synchrotron facility. 

Spent resins are generally compatible with the polymer matrix material. Generally, the polymer and the resin do not interact chemically. The immobilization of spent ion-exchange resins in polymers is a common application all over the world. Epoxy resins, polyesters, polyethylene, polystyrene and copolymers, polyurethane, phenol-formaldehyde, and polystyrene are among the polymers used (IAEA, 1988). Inorganic materials are generally not immobilized using polymers because they are more acceptable to other immobilization matrices such as cement. 

The alkylation of tertiary phosphines is, in general, compatible with elaborate structures bearing various functions or chiralities, as illustrated by the preparation of a phosphonium salt (18), intermediate in the synthesis of pseudomonic acid248 (reaction 17). For the preparation of dialkylphosphonium salts, diphenylphosphine can be directly alkylated, but it is more advantageous to use triphenylphosphine as the starting material,... 

Other experimental values for the angle —are given in Table 4-6. It may be seen that they are in general compatible with the value 113° described above as the normal value. 

The molecular structures adopted by simple carbonyl complexes are generally compatible with predictions based on valence shell electron pair repulsion theory. Three representative examples from the first transition series are shown in Fig. 15.2. 

The primary advantage of the Coomassie plus protein assay is that it is generally compatible with most of the buffers and reagents found in samples and is unaffected by the presence of chelating agents, reducing agents, or free sulf-hydryls in the sample. 

Anelli s protocol is not generally compatible with the presence of olefins,10 although the less reactive olefins conjugated with electron-with-drawing groups, like carbonyls, are not affected,45 and occasional examples in which normal olefins remain unchanged during the oxidation of alcohols are found in the literature.13... 

Direct analysis of the enantiomers in biological fluids is very important because it reduces both analysis time and sample preparation time. Indeed, when there is risk of the quick racemization of the enantiomer, direct analysis is essential. It has been observed that CD-based CSPs employ mobile phases that are generally compatible with biological samples, hence can be used for the direct analysis of the enantiomers in biological fluids [67,80]. Stalcup et al. [58] employed coupled column chromatography to isolate scopolamine from a plant extract and found that the extent of racemization depends on the isolation... 

The definition of categories for the chart is an important part of construction. For small plants and operations, each chemical may be included in the chart and still be of manageable size. For more general compatibility charts the best manner to construct a chart is to group chemicals into natural groupings based on their chemical structure. Examples of these groupings are mineral acids, aliphatic amines, monomers, water-based formulations, halogenated hydrocarbons, etc. 

Phosphate buffer pH range 6-7, 0.05-0.2 M has been found to be generally compatible for extracting most viruses. However, others, including Tris-HCl buffer (0.05-0.1 M, pH range 6.5-7.2), should be tried if results are unsatisfactory (4,11). 

Existing waste classification systems are generally compatible with available data. Compatibility is the result of the databases having been acquired to meet the needs of the waste classification... 

As an inorganic mineral, most unmodified nanoadditives are strongly hydrophilic and are generally compatible and miscible only with a few hydrophilic polymers, for instance, clay can only be made into PNs with polyethylene oxide),27 poly(vinyl alcohol),28 and a few other water soluble polymers. Most polymers are hydrophobic and thus they are neither compatible nor miscible with the unmodified nanoadditives, leading to an inability to achieve a PN with a good nanodispersion in most cases. Therefore, for most nanoadditives that have been used to prepare the PNs, an important and necessary feature is their surface treatment that provides compatibility to the nanoadditives and enables them to be uniformly dispersed (and/or separated into single nanoparticles) in the polymer matrix. 

Addressing large molecular systems is the aim of Chapter 3, which reviews a recently developed model based on the combined use of quantum mechanics and molecular mechanics (QM/MM). This approach uses a fully self-consistent polarizable embedding (PE) scheme described in the paper. The PE model is generally compatible with any quantum chemical method, but this review is focused on its combination with density functional theory (DFT) and time-dependent density functional theory (TD-DFT). The PE method is based on the use of an electrostatic embedding potential resulting from the permanent charge distribution of the classically treated part of... 

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