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Gastrin secretion

Hormonal gastrin secreted by the G cells of the gastric antrum stimulates the parietal cells directly through gastrin receptors (increased Ca2+ as second messenger), and probably also indirectly by acting on enterochromaffin-iike (ECL) cells to release histamine. [Pg.184]

Gastric inhibitory peptide (GIP) Polypeptide (43 residues) Inhibits gastrin secretion... [Pg.573]

GRP 119) 53 was isolated from porcine mucosae and causes gastrin secretion. The C-terminal decapeptide of GRP is, with the exception of His20, identical with that of bombesin 54, and also coincides with the sequence of the decapeptide neuromedin C 119b,c) [Gly18-Met27]-GRP. Neuromedin C, a porcine spinal-cord peptide that can also be regarded as a bombesin-like peptide, exerts stimulating effects on rat uterine smooth muscle and functions as a neuromediator in the neural communication systems of mammals. [Pg.127]

Stimulates insulin release inhibits gastric acid, pepsin, and gastrin secretion reduces gastric and intestinal motihty increases fluid r and electrolyte secretion from small intestine... [Pg.1874]

Octreotide blocks the release of serotonin and many other active peptides and has been effective in controlling diarrhea and flushing. It is reported to have direct inhibitory effects on intestinal secretion and stimulatory effects on intestinal absorption. Non-gastrin-secreting adenomas of the pancreas are tumors associated with profuse watery diarrhea. This condition has been referred to as Verner-Morrison syndrome, WDHA (watery diarrhea, hypokalemia, and achlorhydria) syndrome, pancreatic cholera, watery diarrhea syndrome, and VIPoma. Excessive secretion of VIP from a retroperitoneal or pancreatic tumor produces most of the clinical features. Excessive VIP is isolated in about half of patients, along with numerous other peptide hormones (peptide histidine methionine [PHM], serotonin,... [Pg.682]

ZoUinger-Ellison syndrome—Gastric acid hypersecretory disease caused by a gastrin-secreting tumor and leading to multiple, severe duodenal ulcers. [Pg.2694]

Secretin is a GI function test, which increases the volume and bicarbonate content of secreted pancreatic juices. It is indicated in stimulation of pancreatic secretions, including bicarbonate, to aid in diagnosis of pancreatic exocrine dysfunction stimulation of gastrin secretion to aid in diagnosis of... [Pg.635]

Octreotide inhibits gastrin secretion, whereas drugs such as cimetidine and omeprazole increase it. Octreotide is also extremely costly, making combination therapy with these agents of maximum benefit. [Pg.223]

Acid denaturation Gastrin-secreting islet cell tumor causing... [Pg.141]

Control of Gastric Secretion 259 Mechanisms of Gastrin Release Regulation of Gastrin Secretion... [Pg.245]

Acetylcholine is known to stimulate directly the fundic gland to secrete hydrochloric acid to sensitize parietal cells to the action of gastrin and to stimulate directly gastrin secretion in the pyloric region. [Pg.260]

It is believed that insulin hypoglycemia brings about gastrin secretion by stimulation of the long vagal reflexes. Distension of the stomach is likely to release... [Pg.260]

See other pages where Gastrin secretion is mentioned: [Pg.172]    [Pg.525]    [Pg.170]    [Pg.323]    [Pg.272]    [Pg.377]    [Pg.380]    [Pg.961]    [Pg.255]    [Pg.1019]    [Pg.168]    [Pg.438]    [Pg.794]    [Pg.274]    [Pg.72]    [Pg.525]    [Pg.73]    [Pg.73]    [Pg.519]    [Pg.73]    [Pg.73]    [Pg.519]    [Pg.854]    [Pg.1876]    [Pg.1876]    [Pg.203]    [Pg.208]    [Pg.250]    [Pg.251]    [Pg.253]    [Pg.163]    [Pg.1313]    [Pg.526]    [Pg.199]    [Pg.203]    [Pg.240]    [Pg.229]   
See also in sourсe #XX -- [ Pg.246 , Pg.247 ]

See also in sourсe #XX -- [ Pg.260 ]



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