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Gastric acid secretion gastrin-releasing peptide

Secretin inhibits postprandial gastrin release (thus decreasing gastric acid secretion) and increases pancreatic exocrine secretion (e.g. of bicarbonate). The secretin receptor (like the GLP-1 receptor and vasoactive intestinal peptide (VIP) receptor) acts via Gas and cAMP elevation. A plant agonist for the secretin receptor has been isolated from the Thai anti-ulcer plant Croton sublyratus (plau-loi) (Table 5.8). [Pg.167]

Secretin Enteroendocrine S cells in upper small bowel 1. Stimulates pancreatic and biliary bicarbonate and water secretion 2. Regulates pancreatic enzyme secretion 3. Inhibits postprandial gastric emptying, gastrin release, and gastric acid secretion 1. Gastric acid, bile salts, fatty acids, peptides, and ethanol 2. Somatostatin inhibits secretion... [Pg.801]

Figure 4.2 Gastric add production. Two cell types in the mucosa of the corpus of stomach are principally responsible for secretion of acid. Histamine secreted from nearby enterochromaffin-like (ECL) cells stimulates parietal cells to secrete acid. A variety of substances can stimulate the ECL cell to secrete histamine, including PCAP, pituitary adenyl cyclase-activab ng peptide (released from enteric nervous system interneurones in the gastric mucosa), and gastrin, both stimulating ECL cells via adenyl cyclase to raise intracellular levels of cAMP that lead to histamine secretion. Figure 4.2 Gastric add production. Two cell types in the mucosa of the corpus of stomach are principally responsible for secretion of acid. Histamine secreted from nearby enterochromaffin-like (ECL) cells stimulates parietal cells to secrete acid. A variety of substances can stimulate the ECL cell to secrete histamine, including PCAP, pituitary adenyl cyclase-activab ng peptide (released from enteric nervous system interneurones in the gastric mucosa), and gastrin, both stimulating ECL cells via adenyl cyclase to raise intracellular levels of cAMP that lead to histamine secretion.
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See also in sourсe #XX -- [ Pg.78 ]



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Gastric acid secretion

Gastric secretion gastrin

Gastric secretions

Gastrin

Gastrin secretion

Gastrin-releasing peptide

Peptide releaser

Peptides acids

Peptides release

Secretions Gastric secretion

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