Gastric retention devices

PVP VP was crosslinked by (.lA modified albumin. Degradation of erosslinker by pepsin. Gastric retention device targeted for long-term oral dnig delivery. Shalaby /fl/., 1990, 1991, lt)92, 199.3... 

Superporous hydrogels (SPHs) ate materials developed to demonstrate fastswelling and superabsorbent properties (Omidian et al., 2005). These were initially proposed as gastric retention devices however, SPHs may be tailor-made for other applications in pharmaceutical arxl biomedical industries (Omidian et al., 2007). The high swelling pressure of SPHs can potentially be used to trigger an alarm system upon the incursion of water and hence, can be utilized as smart hydrogels or sensors for various apphcations. 

Gastric bypass surgery, 3 89 Gastric flotation/retention devices, 9 45 Gas turbine oils, 15 235 Gas turbines, 10 142-143... 

Hence, dogs can be considered a good model for initial gastroretentive evaluation of a new device. On the other hand, pigs cannot be considered a proper model as they normally have a longer gastric retention of pellets and ordinary tablets than human. The most important conclusion from all previous studies is that the best model for human is human. " " ... 

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