Gastric function

The gastric juice contains acid at the highest concentration to be found anywhere in the body. It is therefore appropriate to consider the secretion of gastric juice and its influence on the acid-base status of the body. 

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ATC V03AB17 V04CG05 Use diagnostic (for gastric function test),... 

If you look in the medical literature, you will often see the term placebo defined as a non-specific treatment. What does it mean to say that a treatment is not specific It could mean that the treatment is effective for many different disorders, rather than for only one particular condition. In this sense, placebos are indeed non-specific. Besides depression, placebos have been shown to affect anxiety, pain, ulcers, irritable bowel syndrome, Parkinson s disease, angina, autoimmune diseases, Alzheimer s disease, rheumatoid arthritis, asthma, gastric function, sexual dysfunction and skin conditions. We know this from the thousands of studies in which placebos have been used as control conditions, against which the effects of medication have been evaluated, and from studies that were specifically designed to assess the placebo effect. 

Tachibana I Kanagawa K, Yamamoto Y, Otsuki M (1996) Pharmacological profile of a new serine derivative cholecystokinin receptor antagonist TP-680 on pancreatic, biliary and gastric function. J Pharmacol Exp Ther 279 1404-1412... 

Hunt JN, Murray FA. Gastric function in pregnancy. J Obstet Gynaecol Br Emp 1958 65 78-83. 

The activity of the proteolytic enzymes in gastric juice is of great biological significance. New concepts and findings have been recently developed regarding their nature and mutual relation. Other enzymes have played a far less important role in gastric function, or their role in the stomach has not as yet been adequately understood. 

W18. Wolf, S., and Glass, G. B. J., Correlation of conscious and unconscious conflicts with changes in gastric function and structure. Observations on the relation of the constituents of gastric juice to the integrity of the mucous membrane. Proc. Assoc. Res. Nervous Mental Disease 29, 665-676 (1949). 

The gastric phase of protein digestion is not absolutely required for health. Patients lacking gastric function because of a gastrectomy (surgical removal of the... 

Christie, D.L. Development of gastric function during the first month of life. In Infancy Lebenthal, E., Ed. Raven Press New York, 1981 109-120. 

Stewart JJ, Wood MJ, Wood CD, Mims ME. Effects of ginger on motion sickness susceptibility and gastric function. Pharmacology 1991 42 111—120. 

Takeuchi K, Ukawa H, Konaka A, Kita-muraM, Sugawa Y. 1998. Effect of nitric oxide-releasing aspirin derivative on gastric functional and ulcerogenic responses in rats comparison with plain aspirin. J. Pharmacol. Exp. Ther. 286 115-21... 

The mechanisms by which pectin and other viscous fibers affect carbohydrate metabolism have been attributed mainly to the ability of these materials to decrease the rate of carbohydrate absorption within the gastrointestinal tract. This seems to be a result of inhibition of a series of processes associated with lumenal digestion of carbohydrate, including gastric function, intestinal transit and mixing, a-amylase-starch interactions and movement of the hydrolyzed products of starch. A number of physicochemical mechanisms may be involved which of these predominate will... 

Malagelada JR, Longstreth GF, Summerskill WHJ, and Go VLW. Measurement of Gastric Functions During Digestion of Ordinary Solid Meals in Man. Gastroenterol lOlO 70 203-210. 

Newman, A., de Moraes-Filho, J. P., Philippakos, D., Misiewicz, J. J.,The effect of intravenous infusions of prostaglandins E-2 and F-2alpha on human gastric function. Gut 1975, 26, 272-276. 

J. Malagelada, G. Longstreth, W. Summerskill, and V. Go. Measurement of gastric functions during digestion of ordinary solid meals in man. Gastroenterology 70 203 (1976). 

Pathology in Cambridge. Here, he made several useful contributions in research on inflammation, gastric function and secretion of mucus this latter area of research led him on to a major study of lysozyme structure and function that lasted until 1938. From Cambridge, Florey moved to the University of Sheffield as Professor of Pathology in 1932, but this proved to be a brief stay since he was offered the Chair of Pathology at the Sir William Dunn School of Pathology in Oxford three years later. This was to become the focus of penicillin research some four years later. 

Odunsi, S. T., Vazquez-Roque, M. L, CamiUeri, M., Papathanasopoulos, A., Clark, M. M., Wodrich, L., Lempke, M., McKinzie, S., Ryks, M., Burton, D., and Zinsmeister, A. R. (2010). Effect of alginate on satiation, appetite, gastric function, and selected gut satiety hormones in overweight and obesity. Obesity (Silver Spring) 18,1579-1584. 

It is not known how important this interaction is likely to be in practice, but the efficacy of amphotericin B for intestinal candidiasis or gut decontamination may be decreased. Separating the dosages might not be effective in some postoperative patients because their gastric function may not return to normal for up to 5 days, and some sucralfate might still be present when the next dose is given. This study was conducted more than a decade ago, and nobody appears to have conducted a clinical study to establish its hypothesis. If both sucralfate and oral amphotericin are required, it would seem prudent to monitor concurrent use carefully, being alert for any evidence of reduced effects. 

New application examples are coming up all the time, such as imaging of gastric function, pulmonary ventilation, perfusion, brain hemorrhage, hyperthermia, swallowing disorders, and breast cancer. A fundamental difficulty is the considerable anisotropy found in the electrical properties of, for example, muscle tissue. 

Mangnall, Y.R, Baxter, A.J., AviU, R., Bird, N.C., Brown, B.H., Barber, D.C., Seagar, A.D., Johnson, A.G., Read, N.W., 1987. Applied potential tomography a new non-invasive technique for assessing gastric function. Clin. Phys. Physiol. Meas. 8 (Suppl. A), 119—130. 

Acid secretory tests remain the best research tools for investigating normal and abnormal gastric function and the best tests for evaluating the effective suppression of meal-stimulated gastric acid secretion, a mandatory test of the therapeutic effectiveness of antisecretory drugs. Measurement of 24-h intragas-tric pH, a new trend, has become increasingly easier... 

Scarpignato C and Bianchi Potto G (eds.) (1990) Clinical Investigation of Gastric Function. Frontiers of Gastrointestinal Research, vol. 17. Basel Karger. 

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