Gastrointestinal function gastric motility

Gastrointestinal motility is an essential function of the digestive and absorptive processes of the gut. It propels intestinal contents, mixes them with digestive juices, and prepares unabsorbed particles for excretion. Gastric motility has been shown to be inhibited by D-glucose in the intestinal fluid. 

From the studies described above, it is evident that motilides not only stimulate gastric motility but also accelerate delayed gastric emptying in certain clinical conditions. As the next step, the clinical benefit to patients with gastrointestinal disorders (e.g., symptom relief) needs to be proved in double-blind and placebo-controlled studies. Motilides seem to offer an additional therapeutic possibility for the treatment of patients with impaired gastric motor function. 

B. Octreotide also suppresses pancreatic function, gastric acid secretion, and biliary and gastrointestinal tract motility. 

The peripheral effects concern the motility and tonus of gastrointestinal smooth muscle segmentation is enhanced but propulsive peristalsis is inhibited. The tonus of sphincter muscles is markedly raised (spastic constipation). The antidiarrhetic effect is used therapeutically (loperamide, p.180). Gastric emptying is delayed (pyloric spasm) and drainage of bile and pancreatic juice is impeded because the sphincter of Oddi contracts. Likewise, bladder function is affected specifically bladder emptying is impaired owing to an increased tone of the vesicular sphincter. 

Functional ultrasound of the gastrointestinal (GI) tract includes studies of the distal and proximal stomach, gastric and gallbladder emptying, gastric distribution, Gl wall motility, and flow of luminal contents in healthy subjects as well as in patients. Furthermore, it includes the effect of different meals and pharmacological intervention. 

---