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Amphotericin B, oral

Mucocutaneous candidiasis is generally not life-threatening nor invasive and can be treated with topical azoles (clotrimazole troches), oral azoles (fluconazole, ketoconazole, or itraconazole), or oral polyenes (such as nystatin or oral amphotericin B). Orally administered and absorbed azoles (ketoconazole, fluconazole, or itraconazole solution), amphotericin B suspension, intravenous caspofungin, or intravenous amphotericin B are recommended for refractory or recurrent infections.20... [Pg.1223]

There have been few controlled studies that assess the effectiveness of antifungals. Doubling of the fluconazole dosage to 400 or 800 mg/day may be effective in some patients with infection caused by Candida of intermediate resistance, although the response may be only transient. Fluconazole oral suspension may be beneficial in some patients because of increased salivary concentrations obtained when the suspension is taken with the swish-and-swaUow technique. Itraconazole oral suspension is effective in 55% to 70% of patients however, the benefit is short-lived if chronic suppressive therapy is not maintained, and there is a high likelihood of the development of itraconazole resistance. Amphotericin B oral suspension is limited primarily to use in azole-refractory patients It has broad spectrum... [Pg.2155]


See other pages where Amphotericin B, oral is mentioned: [Pg.212]    [Pg.212]   
See also in sourсe #XX -- [ Pg.212 ]




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