Furan 2-ethyl-4-methyl

Other furans included methyl- 2-furfural [4], 2-acetylfuran [5], 2-propionylfuran [6], l-(2-furanyl)-2-propanone [7] and l-(-2-furanyl)-3-butanone [8]. Several alkylpyrazines were also found, with the 2,5-dimethyl [9] and 2-methy 1-5-ethyl [10] the most abundant derivatives, and some 2-acyl-l-methylpyrroles of which only the formyl [11] and acetyl [12] derivatives were conclusively identified. 

SULFONYL)M ETHYL] FUR AN AND 2-METHYL-3-[(PHENYLSULFONYL)METHYL]-2-CYCLOPENTEN-1-ONE (Benzene, [(2,3-dlbromO 1-propenyl)sulfonyl]>, Furan, 2-methyl-4-[(phenylsulfonyl)methyl]-, and 2-Cyclopenten-l-one,... 

Ethyl-isopropenyl- IV/2, 375 Ethenyl-isopropyl- Vl/ld, 147 f. Furan 2-Methyl-tetrahydro- IV/lh, 157 (Cycl.) IV/ld, 226 (Keton-Red.) VI/lb, 611 f. (Jeger-Reakt) VI/3, 529f. (Cyctokond.) Oxetan... 

Bicyclo 4.1.0]heptan 7-Trimethyl-silylcarbonyl- E17b, 1393 (7-Br/7-SiR3 — 7-H/7-CO—SiR3) Cyclohexan trans-2-Hydroxy-1-(trimethylsilyl-ethinyl)- E19d, 146 (sp-CH - C - Li/Oxiran) Cyclopenten 2-Ethyl-4-methylen-l-trimethylsilyl- E17c, 2251 (Methylen-cyclo propan + In) Ethen l-(l-Cyclohexenyl)- -trimethylsilyloxy- E1S/1, 441 (Keton 4- RjSi—O —S02 —R) Furan 2-Methyl-5-propyl-3-trimethylsilyl- E18, 674 (In-Hydromagnesier./+ R —CN)... 

SAFETY PROFILE Stable in dry air at room temperature. It decomposes above 125° forming Al, H2, and lithium hydride. Very powerful reducer. Can ignite if pulverized even in a dry box. Reacts violendy with air, acids, alcohols, benzoyl peroxide, boron trifluoride etherate, (2-chloromethyl furan + ethyl acetate), diethylene glycol dimethyl ether, diethyl ether, 1,2-dimethoxyethane, dimethyl ether, methyl ethyl ether, (nitriles + H2O), perfiuorosuccinamide,... 

Furan, 2-[(ethylthio)methyl]-, 2-[ (ethylsulfanyl) methyl]furan, ethyl (furfuryl) sulfane, ethyl furfuryl sulfide [2024-70-6]... 

It is to be noted that excellent agreement is found between tt and results and the earlier tt values for the following 21 solvents n-hexane, cyclohexane, triethylamine, isopropanol, dioxane, -propanol, ethanol, tetrahydro-furan, ethyl acetate, methyl acetate, ethyl formate, ethanol, methyl orthoformate, 2-butanone, acetone, acetic anhydride, nitromethane, dimethylacetamide, dimethylformamide, sulfolane, and dimethyl sulfoxide. The aromatic and polychlorinated aliphatic solvents give lower rr i and ir 2 results than the uv-based tt values (as expected in the light of the fact that these are really (ir + d5) terms all nmr shifts so far studied have involved negative d values in Equation 95). 

Aiiyi chloride Cl2-16 alcohols 3-Chloro-2-methylpropene N,N -Diphenyl-p-phenylenediamine Ethylbenzene Ethyl mercaptan Furan Hexamethylenediamine Methyl laurate 2-Methyl-1-pentanol... 

Furane Acetone, methyl ethyl ketone Abrasion. Grit or vapor blast, or 100-grit emery cloth, followed by solvent degreasing ... 

H NMR, 4, 561 <65MI31002> Benzo[b]furan-2-carboxylic acid, methyl ester UV, 4, 589 Benzo[b]furan-3-carboxylic acid, 6-chloro-4,5,7-trifluoro-2-methyl-, ethyl ester C NMR, 4, 568 <72JCS(P2)1733> Benzo[b]furan-3-carboxylic acid, 6-cyano-4,5,7-trifluoro-2-methyl-, ethyl ester C NMR, 4, 568 <72JCS(P2)1733>, 569 <72JCS(P2)1733>... 

Furan, tranx-2-ethyl-2,3,4,5-tetrahydro-3-methyl- C NMR, 4, 574 <790MR(12)461)... 

Furan-2-carbonyl chloride, 5-alkyl-3,4-dichloro-synthesis, 4, 690 Furancarboxamides rotational isomerism, 4, 543 Furan-2-carboxylic acid, 5-acetylamino-ethyl ester reactions, 4, 647 Furan-2-carboxylic acid, amino-properties, 4, 708 Furan-2-carboxylic acid, 5-bromo-nitration, 4, 603, 711 Furan-2-carboxylic acid, 3-methyl-methyl ester bromination, 4, 604 Furan-2-carboxylic acid, 5-methyl-nitration, 4, 602... 

Furan-2(3H)-one, 4,5-dihydro-5-methyl-dipole moments, 4, 556 Furan-2(3H)-one, 5-methyl-reactions, 4, 648 Furan-2(5H)-one, 5-alkoxy-synthesis, 4, 135 Furan-2(5H)-one, 5-ethyl-synthesis, 4, 135... 

Bromochloromethane Methyl ether Methyl ethyl ether Methyl ethyl ketone Methyl formate 2-Methyl furan... 

The final variation of the Feist-Benary furan synthesis encompasses reactions of 1,3-dicarbonyls with 1,2-dibromoethyl acetate (52). For example, treatment of ethyl acetoacetate (9) with sodium hydride followed by addition of 52 at 50°C yields dihydrofuran 53. The product can be easily converted into the corresponding 2-methyl-3-furoate upon acid catalyzed elimination of the acetate, thus providing another strategy for the synthesis of 2,3-disubstituted furans. 

Using these assumptions and conventions, Imoto and co-workers have correlated a number of series of reactions of thiophenes and furans. The reactions studied are the acid-base equilibria pK values) and the acid catalyzed methylations (thiophenes only) of thiophene-and furan-carboxylic acids and the alkaline hydrolyses of their ethyl esters the side-chain bromination of the a-acetylthiophenes, and the a-mercuration of thiophenes and the polarographic half-wave potentials of the methyl esters of thiophene- and furan-carboxylic acids and of nitrothiophenes. The pK values were determined and the ester hydrolyses studied for all three substitution orientations in the thiophene series. For the 4-R-2-Y and 5-R-2-Y series, the p-values do not appear significantly different and the data could probably be combined into a single series unfortunately, however, no limits of accuracy are reported for the p-values, and some of the raw data are not readily available so recalculation is not easily possible. For the 5-R-3-Y series the p-values deviate considerably from the other values however, whereas they are higher for the pK values, they are lower for the ester hydrolyses, and it is possible that the differences are neither systematic nor significant. 

Reaction of the potassium salt of salicylaldehyde with chlo-roacetone affords first the corresponding phenolic ether aldol cyclization of the aldehyde with the ketonic side chain affords the benzofuran (1). Reduction of the carbonyl group by means of the Wolf-Kischner reaction affords 2-ethyl-benzofuran. Friedel-Crafts acylation with anisoyl chloride proceeds on the remaining unsubstituted position on the furan ring (2). The methyl ether is then cleaved by means of pyridine hydrochloride (3). lodina-tion of the phenol is accomplished by means of an alkaline solution of iodine and potassium iodide. There is thus obtained benziodarone (4)... 

E) Preparation of 2-( 1-Succinyloxyethyl)-3-Methyl-5-(2-Oxo-2,5-Dihydro-4-Furyl)Bemo[b] -Furan (409 CBj 8.65 grams of compound 3574 CB in 43 ml of pyridine are warmed for 30 minutes, on a water bath, with succinic anhydride. At the end of this, the pyridine is stripped off in vacuo. The mixture is treated with dilute sulfuric acid and with ether, the crystalline product filtered off, washed with water and with ether, and recrystallized from ethyl acetate (9.35 grams). MPq = 144°C (measured after drying at 90°C and 0.1 mm). Yield 77%. The product yields an equimolecular compound with morpholine. MPc= 136°C (from ethyl acetate). 

Ethylene oxide Propylene oxide Butyl vinyl ether Ethyl vinyl ether Methyl vinyl ether Divinyt ether Furfuryl alcohol I.A-Dioxan Furan... 

The S02process. Sand is mixed with a furane polymer resin (1.2 to 1.4% of sand weight) and an organic peroxide (such as methyl ethyl ketone peroxide at 25 to 60% of resin... 

The pyranofurooxazoline 109 can be prepared by a nitrene insertion reaction of the corresponding furan 110 upon treatment with ethyl azidoformate at — 50 °C under photolysis conditions. Compound 109 is moisture sensitive, and upon treatment with wet acidic THF was converted quantitatively to the more polar furanopyran 111. The structure and stereochemistry of 109 were proved unambiguously by X-ray diffraction, showing that the nitrene inserted anti to the bridgehead methyl group <1999JOC736> (Scheme 30). 

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