Functional Proteomics and Genomics

The development of new technologies within functional (and structural) genomics is considered to be an indispensable factor in the development of personalized medicine, which is based on individual approach to a patient. It is assumed that determining an individual genetic profile of a patient will enable safe and efficacious treatment. 

Progress in functional genomics is related to combining its methods with applications for automatic analysis of protein enzymatic activity and occurrence, accompanied by detection of protein products by means of 2D electrophoresis and mass spectrometry. This will enable detection of mRNA and protein as gene expression product, as well as comprehensive research of the relationship between genetic polymorphism, and individual and environmental factors (such as allergen or treatment exposure). 

Comprehensive genomic research therefore necessitates a combination of several advanced techniques (technologies) which would form more complex technological lines. An example of such solutions may be found in recent scientific papers (Pawliczak and Shelhamer, 2003 Braga-Neto and Marques, 2006)  

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