Functional lipidomics

Bowers-Gentry R. C., Deems R. A., Harkewicz R., and Dennis E. A. (2006). Eicosanoid lipidomics. In Feng L. and Prestwich G. D. (eds.), Functional Lipidomics. CRC Press-Taylor Francis Group, Boca Raton, pp. 79-100. 

Feng L, Ferguson C, Nielsen PO, Chakravarty L, Rzepecki PW, Prestwich GD (2006) Methods of probing phosphoinositides-protein interactions. In Feng LP, Prestwich GD (eds) Functional lipidomics. Taylor Francis, Boca Raton, FL, pp 215-274... 

Feng, L. and Prestwich, G. D. (2006) Functional Lipidomics. CRC Press, Taylor Francis Group, Boca Raton... 

Taki, T. 2013. Bio-recognition and functional lipidomics by glycosphingolipid transfer technology, Proc. Jpn. Acad. Ser. B Phys. Biol Scl, 89 302-320. 

The term lipidome first appeared in the literature in 2001 [25]. In 2002, Ril-fors and Lindblom [54] coined the term functional lipidomics as the study of the role played by membrane lipids. In 2003, the field bloomed with different definitions [41, 55], demonstrations of technologies [41, 56], and biological applications [41, 57, 58]. Han and Gross first defined the field of lipidomics through integrating the specific chemical properties inherent in lipid species with a comprehensive mass spectrometric approach [41]. Since then, all areas of the field have been greatly accelerated. 

Gross, R.W., Jenkins, C.M., Yang, J., Mancuso, D.J. and Han, X. (2005) Functional lipidomics The roles of specialized hpids and Upid-piotein interactions in modulating neuronal function. Prostaglandins Other Lipid MediaL 77, 52—64. 

Guichardant, M., Chen, R, Liu, M., Calzada, C., Colas, R., Vericel, E. and Lagarde, M. (2011) Functional lipidomics of oxidized products from polyunsaturated fatty acids. Chem. Phys. Lipids 164, 544-548. 

Feng L, Prestwich GD, editors. Functional lipidomics. New York Marcel Etekker—CRC 2005. 

Recent developments in mass spectrometry, particularly the introduction of the ESI method, have paved way to functional lipidomics, i.e., the use of detailed lipid profile of cell or tissues to unravel biological phenomena and the mechanisms underlying various metabolic perturbations or diseases. 

Schmitz G, Liebisch G, Langmann T (2006) Lipidomic strategies to study structural and functional defects of ABC-transpoiters in cellular lipid tr afficking. FEBS Lett 9 5 80(23) 5597-610. Review... 

TARGETED LIPIDOMICS AS A TOOL TO INVESTIGATE ENDOCANNABINOID FUNCTION... 

Targeted lipidomics is leading to a better understanding of endocannabinoid metabolism. Recent innovations in LC/MS analyses have led to the rapid identification and quantification of numerous lipids, and these data are creating new opportunities to enhance our knowledge of endocannabinoid function in the context of lipid metabolism. 

Hla, T. Genomic insights into mediator lipidomics.. Prostaglandins Other Lipid Mediat. 2005 77 197-209. www.lipidlibrary.co.uk is a reference website with up-to-date information on the structure, function, and analysis of lipids. www.xpharm.com is a database containing pharmacology reference information. 

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