Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Frequency-domain photon migration

A method for on-line monitoring of particle size distribution and volume fraction in real time using frequency domain photon migration measurements (FDPM) has been described. In FDPM the time dependence of the propagation of multiply scattered light provides measurement of particle size distribution and volume fraction. The technique has been applied to a polystyrene latex and a titanium dioxide sluny at volume concentrations in the range 0.3 to 1% [341]. [Pg.606]

The technique is fast and the equipment relatively inexpensive. Moreover, since photon migration measures the time it takes for light to travel through the sample rather than the intensity of the detected signal, it is self-calibrating. [Pg.607]

Frequency domain photon migration (FDPM) has been investigated as an optical technique with potential application to particle size analysis,67 albeit in a laboratory environment. The approach could be readily implemented in situ, with appropriate... [Pg.344]

Sun, Z. Torrance, S. McNeil-Watson, F.K. etal., Application of frequency domain photon migration to particle size analysis and monitoring of pharmaceutical powders Anal. Chem. 2003, 75, 1720-1725. [Pg.359]

Pan, T. 8t Sevick-Muraca, E.M., Volume of pharmaceutical powders probed by frequency-domain photon migration measurements of multiply scattered light Anal. Chem. 2002, 74, 4228M234. [Pg.442]

Sun, Z. Huang, Y. Sevick-Muraca, E.M., Precise analysis of frequency domain photon migration measurement for characterization of concentrated colloidal suspensions Rev. Sci. Instrum. 2002, 73, 383-393. [Pg.442]

NIR is not the only technology available for blend monitoring, Ught-induced fluorescence (LIF) [11] has also been used as has frequency domain photon migration (FDPM) [12, 13]. A second type of formulation process is wet granulation. In wet granulation a dry excipient blend is dosed with API and wetted under shear to form particles of known size, each of which contain the... [Pg.350]

The separation of absorption and scattering often requires specific types of instrumentation, based on the theoretical approach that is used. In this section, four main designs will be discussed integrating sphere-based reflectance and transmittance, spatially resolved spectroscopy, time-resolved spectroscopy, and frequency domain photon migration. [Pg.27]

Richter, S. M., Shinde, R. R., Balgi, G. V., Sevick-Muraca, E. M., Particle Sizing Using Frequency Domain Photon Migration, Part. Part. Sy r. Charact, 1998, 15,9-15. [Pg.107]

Phase shift fluorimetry, the other important method for measuring fluorescent lifetimes, also continues to be developed and improved. The effects of Inaccurate reference lifetimes on the interpretation of frequency domain fluorescence data can be removed or minimized by a least squares analysis method.The direct collection of multi-frequency data for obtaining fluorescence lifetimes can be achieved by the use of digital parallel acquisition in frequency domain fluorimetry. Frequency domain lifetime measurement has been used for on-line fluorescence lifetime detection of eluents in chromatography. An unusual use of frequency domain measurement which has been reported is for the examination of photon migration in living tissue. Photons in the... [Pg.7]

See other pages where Frequency-domain photon migration is mentioned: [Pg.430]    [Pg.431]    [Pg.468]    [Pg.606]    [Pg.28]    [Pg.323]    [Pg.100]    [Pg.405]    [Pg.430]    [Pg.431]    [Pg.468]    [Pg.606]    [Pg.28]    [Pg.323]    [Pg.100]    [Pg.405]    [Pg.490]    [Pg.555]   
See also in sourсe #XX -- [ Pg.606 ]

See also in sourсe #XX -- [ Pg.100 ]



SEARCH



Frequency domain

Frequency domain photon

Frequency domain photon migration FDPM)

Photon migration

© 2024 chempedia.info