Free Fatty Alcohols

Free fatty alcohols are perhaps the most common components of cuticular waxes and often are also a major constituent of suberin-associated waxes (232). ThQr comprised between 10% and 45% of the waxes from the periderm of underground storage organs (116). The dominant chain lengths of free fatty alcohols of cuticular waxes are C26 and C28 (232, 253, 292, 460), but the free fatty alcohols of suberin-associated waxes usually have a shorter chain length. For example, the dominant alcohols in the leaf cuticular wax of Agave americana were (36% of the alcohols) and C28 (62%), whereas the dominant component in the fatty alcohols of the suberin-associated wax from the periderm layer surrounding the crystal idioblasts within the same leaf was C22 (88%) (117). The most common fatty alcohols reported as components of bark wax are C24 and C22. 

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Sensitivity is thought to be associated with the content of free fatty alcohols present in lanolin products rather than the total alcohol content. The safety of pesticide residues in lanolin products has also been of concem. However, highly refined hypoallergenic grades of lanolin and grades with low pesticide residues are commercially available. See also Section 18. 

The lanolin allergens are natural free fatty alcohols. Their allergenecity is increased by the simultaneous presence of detergent. Removal of the free fatty alcohols and detergent from lanolin reduced the hypersensitivity by 96% in selected lanolin-sensitive patients (Clark et al. 1977). 

The fatty acid methyl esters C16.0, C18.0, and C18.2 indicate the presence of a vegetable oil. However, the detection of isopropyl palmitate (IPP) and isopropyl stearate (IPS) in the Py-GC experiment (not shown) means that there would also be a contribution of their fatty acids to this pyrogram. The methyl ethers of cetyl alcohol (C16-OME) and stearyl alcohol (C18-OME) suggest the presence of the respective free fatty alcohols, and this is confirmed by an inspection of the pyrogram from the Py-GC experiment (not shown). Myristyl alcohol methyl ether (C14-OME) and myris-tic acid methyl ester (CM. 0) originate from myristyl myristate used in the formulation. 

Species Squalene Sterols Sterol esters Wax esters Diesters Glyceryl ethers Triacyl- glycerols Free fatty acids Free fatty alcohols... 

This is an alternative to the procedure given in section 5.12.2. The mono-and dialkylsulphosuccinates are sorbed on a strongly basic anion exchanger chloride. The eluate contains the aspartate and free fatty alcohols. If desired, the fatty alcohols can be removed by extraction with petroleum ether from acid solution. The aspartate is determined by titration with sodium dodecyl sulphate. 

Saraca indica Hydrocarbons (C29, 46< 7o even-chain length), wax esters (C26 acid and alcohol), free fatty alcohols ( 25, 25) 23... 

U.S.P. United States Pharmacopoea VOLATILE OILS. Scc essential oils vsv. Vesicular stomatitis virus WAXES. Esters of fatty acids with alcohols, both of high molecular weight and straight-chained. But in reality waxes also contain free fatty acids, free fatty alcohols, and hydrocarbons. They are extensively used in pharmaceutical and cosmetic ointments, creams, and lotions... 

Chem. Analysis Free amine HCI4% max. free fatty alcohol 5% max. 

Chem. Analysis Sodium chloride 0.01-0.1% sodium sulfate 0.10-0.70% free fatty alcohol 0.10-0.6%... 

Chem. Analysis TEA chloride 0.3-1.0% free amine 2.0% max. free fatty alcohol 2.0% max. 

Pollerberg, J., Chromatographic determination of free fatty alcohols in their ethoxylation products (in German), Fette, Seifen, Anstrichm., 1966,68,561-562. 

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