Fluorotelomer alcohols properties

In general, the synthesis of polyphosphazene polymers is unique in that, in theory, an infinite number of polymers with a variety of properties can be derived from the common polymeric intermediate, poly(dichlorophosphazene) (PNCI2), by replacing the chlorines with different nucleophiles. If the polydichlorophosphazene precursor is reacted with the sodium salts of trifluoroethanol and a mixed fluorotelomer alcohol, a poly(fluoroaIkoxyphosphazene) elastomer (FZ elastomer) is obtained. It contains a small amount of an unsaturated substituent as a curing site. The polymer is a soft gum, which can be compounded with carbon blacks and fillers and cured with sulfur or peroxides or by radiation. 

Abstract In the past years, elucidation of transformation products of per- and polyfluorinated chemicals (PFC) has been a task frequently approached by analytical chemists. PCT, such as perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) are persistent and thus, the analytical quest to detect transformation products has failed so far. Their prominence as contaminants is mainly due to their extreme persistence, which is linked to their perfluoroalkyl chain length. Molecules that are less heavily fluorinated can show very complex metabolic behavior, as is the case for fluorotelomer alcohols. These compounds are degraded via different but simultaneous pathways, which produce different stable metabolites. Biotransformation processes of PFC may occur when these compounds enter the environment, and thus known and unknown PFC may be generated in these compartments. Therefore, it is essential to determine metabolic pathways of such compounds in order to entirely understand their fate in the environment. This chapter summarizes methodological approaches and instmmental setups which have been implemented in biotransformation studies of PFC and focuses on mass spectrometric methods and the separation techniques coupled to the mass spectrometer (MS). Valuable MS approaches that have not been frequently used in studies on PFC are presented as well. Since compounds carrying C-F bonds exhibit unique properties, these will be initially presented to address the meaning of these properties both for analytical tasks and for the setup of biotransformation experiments. 

Loveless SE, Hoban D, Sykes G et al (2008) Evaluation of the immune system in rats and mice administered linear ammonium perfluorooctanoate. Toxicol Sci 105(l) 86-96 Lundin JI, Alexander BH, Olsen GW et al (2009) Ammonium perfluorooctanoate production and occupational mortality. Epidemiology 20(6) 921-928 Maras M, Vanparys C, Muylle F et al (2006) Estrogen-like properties of fluorotelomer alcohols as revealed by MCF-7 breast cancer cell proliferation. Environ Health Perspect 114(1) 100-105 Melzer D, Rice N, Depledge MH et al (2010) Association between serum perfluorooctanoic acid (PFOA) and thyroid disease in the US National Health and Nutrition Examination Survey. Environ Health Perspect 118(5) 686-692... 

Selected organic contaminants covering a wide range of partitioning properties, including polycyclic aromatic hydrocarbons (PAHs), polychlorinated biphenyls (PCBs), hexachlorocyclohexanes (HCHs), fluorotelomer alcohols (FTOHs), chemicals from the BTEX group, light aldehydes (formaldehyde, acetaldehyde), and acetone... 

Uses Fluorochemical intermediate for paints/coatings, printing inks, textiles, metals, plastic films and parts with low surf, energy, chem. and moisture resist., oil/grease resist., low ref. index, and surf, lubricity Properties Purple liq. to semisolid very sol. in acetone, MEK sol. in trichloroethylene, isobutyl alcohol m.w. 553 sp.gr. 1.7 (40 C) vise. < 7 cps (65 C) thickening pt. 25-40 C b.p. 95-185 C (50 mm) 56.1% F Precaution DOT corrosive liq. self-extinguishing Zonyl TELB-N [DuPont DuPont Canada] them. Descrip. Fluorotelomer... 

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