9-hydroxy-9- fluorene

The electron-withdrawing power of the tnfluoromethyl group in the 2,2,2-tri-fluoroethyl ether of 9-hydroxy-9-(dinitromethyl)fluorene considerably retards its hydrolysis compared with simple alkyl ethers [59] (equation 57)... 

Trimethyl-phenyl)-iithanol1 /-Hydroxy-5,6-dimethyl-acenaphthen1 9-Hydroxy-fluoren 4... 

Henkel B, Bayer E. 9-Hydroxy-9-(4-carboxyphenyl)fluorene—a new linker for solid phase synthesis. Tetrahedron Lett 1998 39 9401-9402. 

Barriers to rotation of 9-(2-hydroxy-l-naphthyl)fluorene benzoates (65) reveal... 

Barriers to Rotation and Equilibrium Constants of 9-(2-Hydroxy-l-naphthyl)fluorene Benzoates (65) in Chloroform-d at 69°C... 

In mice, also, deacetylation is involved in the hepato-carcinogenesis induced by 2-(acetylamino)fluorene. Indeed, BNPP-inhibited DNA-adduct formation in murine liver microsomes as well as tumor initiation by A-hydroxy-2-(acetylamino)fluorene in infant male B6C3Fj mice [100],... 

Hydroxy-9-fluorenone, see Fluorene Hydroxyglutaric acid, see Cyclohexene... 

Di( berizoperoxyj-9,9 -fluotene Peroxide [Bibenzo-ate of 9,9 Di(hydroperoxy) 9,9 fluorene Peroxide designated in Ref 2,p 15 as wBibenzoac des Per-oxyds XX ] [called Peroxybenzoic Acid,Diester with Bis(9-hydroxy-9-[luorenyl)-peroxide in CA Formula Index for 1950],... 

Thermochemical data are available (Ref 2) on the heats of combustion and formation for all five isomers, on the heats of nitration from various Dinitrotoluenes for the 23,4-, 2,4,5-, and 2,3,6-isomers, and on the heats of crystn for the 2,3,4- and 2,4,5-isomers. Data are also available (Ref 1) on the shock sensitivities of all of the isomers except 2,3,6-, and on the rates of decompn at 140° of the 23,4-, 2,4,5-, and 23,5-isomers. The detonation pressure and the temp coefficient of decompn between 140 and 180° have been measured for the 2,4,5-isomer 2,3,4- and 2,4,5-TNT form addition compds ( 7r-complexes ) at 1 1 molar ratio with several polycyclic aromatic hydrocarbons (naphthalene, acenaphthene, fluorene, phenanthrene and anthracene) (Ref 2). 2,4,5-TNT forms complexes with 4-aminozaobenzene, 4-aminoacetophenone, bis (2 hydroxy ethyl) amine, and tris (2-hydroxy-ethyl) amine (Ref 1). The first two have a 1 1 molar ratio, the third 1 2, and the fourth 2 1. Upon heating, the two 4-amino compds react with replacement of the 5-nitro group, as discussed below... 

To a solution of the S-(+)-4-acethoxy-9-[2-(5-ethyl-l,2,3,6-tetrahydro-pyridin-3yl)-l-(lH-indol-2-yl)-l-methoxycarbonyl-ethyl]-3a-ethyl-5-hydroxy-8-methoxy-6-methyl-3a,4,5,5a,6,ll,12,12b-octahydro-lH-6,12a-diaza-indeno[7,l-ca]fluorene-5-carboxylic acid methyl ester in dioxane and glacial acetic acid was added 37% aqueous formaldehyde and the mixture stirred at 35°C for 24 h. The solution was evaporated in vacuo and the residue suspended in chloroform and washed with cold aqueous 5% K2C03 solution. The chloroform layer was dried (MgS04), filtered, and evaporated. The residue was chromatographed eluting with EtOAc/MeOH, 10% NH4OH to give the product navelbine. 

The 9-carbonyl group of diazafluorenones behaves in an analogous manner to that in fluorenone reduction to the 9-ol and to the fluorene <70AJC1023>, reaction with dialkyl phosphites to yield 9-hydroxy-9-phosphonic esters <84JPR349>, and with acetone to give the 9-hydroxy-9-(2-oxopropyl) analogue <62CB2137>. 

The first, unequivocal evidence for N-hydroxylation of an aromatic amine in vivo was obtained with 2-(acetamido)fluorene, which was detected in urine as its N-hydroxy derivative almost entirely in the form of a D-glucuronic acid conjugate (that could be cleaved by /3-d-glucosiduronase), to which structure 133 was assigned.362,383 Activation of chemical carcinogens (that are not themselves reactive, but are... 

Beginning with 9-fluorene carboxylic acid, high molecular weight poly(9-hydroxy methyl-9-fluorene carboxylic acid) has been prepared by the homopolymerization of 9-hydroxymethyl-9-fluorene carboxylic acid using trifluoro methanesulfonate as the catalyst. This polymeric agent readily formed donor-acceptor complexes with 1,3-dinitrobenzene and is suitable as a charge transport material. 

Hydroxy-9-fluorene carboxylic acid was also prepared. 

Photogeneration efficiencies of 4,4 -(9-oxo-9H-fluorene-2,7-diyl)bis(azo)-bis[N-(2-chlorophenyl)-3-hydroxy-2-naphthalenecaiboxamide] (AZO-FO) in single- and dual-layer configurations were measured by Umeda et al. (1990). The dual-layer materials contained 4-N,N-bis(4-methylphenyl)amino-a-phenyl-stilbene (MAPS) in the transport layer. Figure 5 shows the field dependencies. 

SYNS FLUORENYL-2-ACETHYDROXAMIC ACID N-FLUOREN-2-YLACETOHYDROXAMICACID N-2-FLUORENYLACETOHYDROXAMICACID N-HYDROXY-AAF N-HYDROXY-2-ACETAXODO-FLUORENE 2-(N-HYDROXYACETAMIDO)-FLUORENE N-HYDROXY-2-ACETYLAMINO-FLUORENE N-HYDROXY-2-FAA O N-HYDROXY-N-(2-FLUORENYL)ACETAMIDE NOHFAA... 

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