Fine, William control

Metals at the active sites of metalloproteins display special properties and are generally impressively efficient in their functional roles. The metal or metals are said to be poised for catalytic action or in an entatic state, an expression first used by Vallee and Williams in their seminal paper of 1968 (2). The fine tuning or control of the peptide in many cases results in previously unobserved aspects of the coordination chemistry of the metal in question. There are many examples, almost as many as there are metalloproteins, from (in the case of Fe) the five-coordinate high-spin Fe(II) in myoglobin and hemoglobin... 

While at the Naval Ordinance Laboratory in White Oak, Maryland, William T. Fine submitted a 1971 report titled Mathematical Evaluations for Controlling Hazards. Fine was an early proponent of determining whether the expenditure needed to substantially reduce risk could be justified after considering the amount of reduction to be attained. 

The risks upcoming from vertical infrastructures (streetlights, traffic lights, walls, etc.) near the trench were evaluated by William Fine s method as Acceptable and by NTP330 as for correction and controller actions . This situation is repeated all over the risk evaluation work. 

Larval development is so finely controlled, that the general belief has been that a minor disruption may result in a major effect for the insect. Disruption of the endocrine system for insect control was first proposed by Williams (19,20), Considerable attention has been paid to JH analogs (JHAs) for insecticidal use in the field. The JHAs have been exploited for control of a number of pest insects including stored product pests, fleas and mosquito larvae (21,22). 

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