Fibroblast growth factors tissue localization

Distribution of basic fibroblast growth factor in the 18-day rat retus localization in the basement membranes of diverse tissues. J. Cell Biol. 110 753-765. 

Weise, B., Unsicker, K. and Grothe, C. (1992) Localization of basic fibroblast growth factor in a subpopulation of rat sensory neurons. Cell Tissue Res. 267 125-130... 

Local intramuscular injection of plasmid DNA or adenoviral vectors encoding vascular epithelial growth factor or fibroblast growth factor, both able to induce the formation of new blood vessels, have been used to improve microcirculation in ischemic tissue. Needle injection of plasmid DNA has been used in leg muscle, catheter application or needle injection was also tried in ischemic heart muscle. The formation of new blood vessels and an improvement in the microcirculation has been observed. 

Kimura, Y., Hokugo, A., Takamoto, T., Tabata, Y., Kurosawa, H., 2008. Regeneration of anterior cruciate ligament by biodegradable scaffold combined with local controlled release of basic fibroblast growth factor and collagen wrapping. Tissue Eng. Part C Methods 14, 47-57. 

Kang, C.E., Baumann, M.D., Tator, C.H., ShoicheL M.S., 2013. Localized and sustained delivery of fibroblast growth factor-2 from a nanoparticle-hydrogel composite for treatment of spinal cord injury. Cells Tissues Organs 197 (1), 55-63. 

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