Fetal origin

Fetal Origins of Cardiovascular and Lung Disease, edited by David J. P Barker... 

Cooper C, Javaid MK, Taylor P, Walker-Bone K, Dennison E, Arden N (2002) The fetal origins of osteoporotic fracture. Calcif Tissue Int, 70 391-394. 

Barker DJP (1995). Fetal origins of coronary heart disease. British Medical Journal 311 171-174... 

There are several acquired hematological disorders which have an increased synthesis of Hb-F [summarized in (H37, K13)], Thus, an elevated level of Hb-F is frequently observed in, for example, Fanconi s anemia, megaloblastic anemia, polycythemia vera, various types of leukemia, multiple myeloma and lymphomas, macroglobulinemia, and metastatic disease of the bone marrow. The chemical heterogeneity of the Hb-F in some of these disorders (aplastic anemia, Fanconi s anemia, and various forms of leukemia) has been studied (H60, R29). In many instances, the to ratio is similar to that found in the normal newborn. This is particularly striking for patients with various forms of leukemia, and the Hb-F which is produced in increased quantities in these disorders invariably has a °y to y ratio of about 3 1. This newborn ratio of °y to y chains in Hb-F may be a common factor in these diseases as perhaps another example of fetal characteristics in red cells of patients with leukemia, it supports the hypothesis that these cells may be of fetal origin (H25). 

Christner PJ, Artlett CM, Conway RF, Jimenez SA (2000) Increased numbers of microchimeric cells of fetal origin are associated with dermal fibrosis in mice following injection of vinyl chloride. Arthritis Rheum, 43 2598-2605. 

Kajantie, E. (2006). Fetal origins of stress-related adult disease. Ann. N. Y. Acad. Sci. 1083 11—27. 

Phillips, D. I. W. (2002), Endocrine programming and fetal origins of adult disease. Trends Endocrinol. Metah. 13, 363. 

Pulmonary and Peripheral Gas Exchange in Health and Disease, edited by J. Roca, R. Rodriguez-Roisen, and P. D. Wagner Lung Surfactants Basic Science and Clinical Applications, R. H. Natter Nosocomial Pneumonia, edited by W. R. Jarvis Fetal Origins of Cardiovascular and Lung Disease, edited by David J. P. Barker... 

Yajnik CS. 2001. The insulin resistance epidemic in India Fetal origins, later lifestyle, or both Nutr Rev 59 1-9. 

Henriksen, Tore, and Torun Clausen. 2002. The Fetal Origins Hypothesis Placental Insufficiency and Inheritance versus Maternal Malnutrition in Well-Nourished Populations. Acta Ohstetricia et Gynecologica Scandinavica 81 112-114. 

Lucy R. Green, B.Sc., Ph.D. Cenlre for Fetal Origins of Adult Disease, University of Southampton, and Prineess Anne Hospital, Southampton, England... 

Once fetal thyroid function starts, the extrathyroidal pools of T4 and T3 in the fetus are of dual maternal and fetal origin 1 -18 normal maternal contribution of T4 is important for the fetal brain in... 

It is suggested that must of the pregnanediol prasent in the placental compartment Ls of fetal origin. 

Furthermore, as the concentration of total 16at-bydroxydchydroepi-aiidrosterone in the maternal plasma is only of the order of 7 Mg/100 ml (Colis et al., 1964), it is concludcid that most of the estriol precursors produced during pregnancy are of fetal origin (sc( Section III, G, 2). 

Vickers, M.H., B.H. Breier, W.S. Cutfleld, P.L. Hofinan and P.D. Gluckman, 2000. Fetal origins of hyperphagia, obesity and hypertension and postnatal amplification by hypercaloric nutrition. Am J Physiol. Endocrinol. Metab. 279, E83-87. 

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