Ferula communis

A number of plant extracts and compounds have potent antimycobacterial properties. Examples of the species that appear to be among the most active include Allium sativum, Borrichia frutescens, Ferula communis, Heracleum maximum, Karwinskia humboldtiana, Leucas volkensii, Moneses uniflora, Oplopanax horridus, Salvia multicaulis, and Strobilanthus cusia. (Newton et al 2000). 

Ferula communis (Umbelliferae) Saudi Arabia Rhizome Active... 

Carmava, A. (1958). Is 3-methyl-4-hydroxycoumarin the active principal to which we attrihute the h poprothromhinizing action of Ferula communis. Boll. Chim. Farm. 97(4) 207-12. 

Carta, A. (1951). Ferulosis isolation of the substance with hypoprothrombinemizing action from the galhanum of Ferula communis. Boll. Soc. Ital. Biol. Sper. 27(5) 690-3. 

Lamnaouer, D. (1999). Anticoagulant activity of coumarins from Ferula communis L (review). Therapie54(6) 747-51. (In French)... 

Mazzetti, G., Cappelletti, G.A. (1957). Effect of the active principle of Ferula communis on blood coagulation thromboe-lastographic study. Arch. Sci. Med. (Torino) 104(3) 236 5. 

Very complex alkynes (1, 2) were isolated from the roots of Ferula communis and their structure was deduced from H-NMR, C-NMR ID and 2D spectra (one bond and long range interactions) . 

C24H30O3, Mr 366.50, colorless cryst., mp. 61 °C. 3-Famesyl-4-hydroxycoumarin from Ferula communis, an Umbelliferous species occurring in the Mediterranean region has significance for homeopathic medicine. Its high toxicity for domestic animals is a frequent cause of problems in the animal breeding industry I... 

C24H30O3 M 366.499 Constit. of the latex of Ferula communis. Shows haemorrhagic action. Mp 64-65 . 

Cannava, a. Is 3-Methyl-4-hydroxycoumarin the Active Substance Responsible for the Hypoprothrombinemia Produced by Ferula communis Boll. chim. Farm. 97, 207 (1958) Chem. Abs. 52, 18689 (1960). 

Carboni, S., V. Malaguzzi, and A. Marsili Ferulenol, a New Coumarin Derivative from Ferula communis. Tetrahedron Letters 1964, 2783. 

Markownikoff cyclization of 353 is represented by maaliol (360), a component of Maali resin, a soft exudate from Canarium samonense (275 vol. Illb). A related compound is maalioxide (361) from roots of Valeriana wallichii (305). Rearrangement of maaliane cation 355 (cf. Fig. 8.1.11), as shown in Fig.8.1.16, leads to the carbon skeleton of aristolene (362), which occurs in the essential oil from roots of Nardostachys jatamansi. (-i-)-Aristolene (a-ferulene) is present in the latex of Ferula communis (312). From roots of Aristolochia debilis, hydroxyketone 363 has been isolated (241). 

From Ferula communis subsp communis (compound 20) [7905]. 

Costa, A., 1950b. Hemorrhagic diathesis from the juice of the roots of Ferula communis behavior of the fibrinogen. Boll. Soc. Ital. Biol. Sper. 26 (7), 1041-1042. Craciun, A.M., Groenen-van Dooren, M.M., Vermeer, C., 1997. Nutritional vitamin K-intake and urinary gamma-carboxyglutamate excretion in the rat. Biochim. Biophys. Acta 1334 (1), 44-50. 

Ferula communis L. Foeniculum vulgare Mill. Fleracleum sphondyllum L. 

Appendino, G., Tagliapietra, S. and Nano, G.M. (1993) An anti-platelet acetylene from the leaves of Ferula communis. Fitoterapia, 64, 179. 

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