Fast cyclic voltammetry Electrochemical detection

Another voltammetric method, sinusoidal voltammetry (SV), was also employed. This was a frequency-based electrochemical method, which was found to be more sensitive than the usual constant potential (DC) amperometric detection method. SV has been achieved to detect on-chip separated catecholamines. This method is very similar to fast-scan cyclic voltammetry (CV), except that a... 

The preparative reduction, polarography, and cyclic voltammetry of 5-methyl-l,2-dithiole-3-thione have been studied.171 The results obtained are in agreement with a one-electron reduction of the thiocarbonyl group to a radical-anion, which could not be detected by ESR spectroscopy as it dimerizes too fast. The dimer is further reduced by a one-electron reduction to an anion in which the ring has been opened. (Scheme 12). The dianion could be isolated after methylation and was found to be identical with the compounds isolated by Maignan and Vialle by reduction with sodium sulfide.124 The dianion corresponds to the thioketonate dianion obtained by electrochemical reduction of 1,2-dithiolylium salts.172... 

FLD = fluorescence detection, LIF = light induced fluorescence, LOD = limit of detection, LC = liquid chromatography, ECD = electrochemical detection, PFET = photoluminescence following electron transfer, MS/MS = tandem mass spectrometry, CE = capillary electrophoresis, FSCV = fast-scan cyclic voltammetry. 

Zachek MK, Hermans A, l ghtman RM, McCarty GS. Electrochemical dopamine detection comparing gold and carbon fiber microelectrodes using background subtracted fast scan cyclic voltammetry. J Electroanal Chem 2008 614 113—20. 

The literature data present some examples of sensors for the detection of several antibiotics and antihypertensive and anti-inflammatory drugs currently used in urban areas. The detection of antibiotic residues in environmental samples through the use of various disposable electrochemical sensors has proved the capacity of these sensors for fast, low-cost, and sensitive detection. Tetracyclines, as an important class of antibiotics, were investigated on gold SPEs using cyclic voltammetry... 

Even at very low applied potentials oxidations of 5-HT leads to formation of some tryptamine-4,5-dione (B, Figure 8). The way in which this can be formed is by electrochemical oxidation (le, 1H+) of primary radical 1 to quinone imine 6 (Figure 8). This electron-deficient molecule cannot be detected by fast-sweep cyclic voltammetry at low pH and so must be rapidly attacked by water to give 4,5-DHT or by HCl to give 4-chloro-5-hydroxy-... 

Controlled potential techniques have shown to be useful tools to characterize the electrochemical behavior of organic compounds. Particularly, cyclic, convolution and square wave voltammetries, controlled potential electrolysis, and digital simulation provide valuable information, which allows elucidating the electrochemical reaction mechanism, and the determination of thermodynamic, kinetic and diffusion parameters (Bard Faulkner, 2001). In addition, the square wave voltammetry is particularly a fast and sensitive technique to detect and quantify a given substrate considering its ability to discriminate against capacitive currents (Osteryoimg O Dea, 1987 Mirceski, Komorsky-Lovric Lovric, 2007). 

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