Factors influencing growth rate

INTERSTRAIN ODOR PREFERENCES AND FACTORS INFLUENCING GROWTH RATES OF TWO STRAINS OF MICE AND THEIR HYBRIDS... 

Interstrain Odor Preferences and Factors Influencing Growth Rates... 

Nucleation and Growth (Round 1). Phase transformations, such as the solidification of a solid from a liquid phase, or the transformation of one solid crystal form to another (remember allotropy ), are important for many industrial processes. We have investigated the thermodynamics that lead to phase stability and the establishment of equilibrium between phases in Chapter 2, but we now turn our attention toward determining what factors influence the rate at which transformations occur. In this section, we will simply look at the phase transformation kinetics from an overall rate standpoint. In Section 3.2.1, we will look at the fundamental principles involved in creating ordered, solid particles from a disordered, solid phase, termed crystallization or devitrification. 

Genetic factors influence the rate of not only synthesis of proteins but also their breakdown, i.e., the rate of turnover. As we have seen in Chapter 10, some enzymes are synthesized as inactive proenzymes which are later modified to active forms, and active enzymes are destroyed, both by accident and via deliberate hydrolytic pathways. Protein antienzymes may not only inhibit enzymes but may promote their breakdown.35 An example is the antienzyme that controls ornithine decarboxylase, a key enzyme in the synthesis of the polyamines that are essential to growth.36,37 As with all cell constituents, the synthesis of enzymes and other proteins is balanced by degradation. 

The CF biological effect on growth stimulation was detected also in dispersed cell culture, in which the contact between cells is avoided by moving liquid culture. It is known that in suspension culture the growth rate is different, with respect to the solid culture one, because cells are subjected to different factors influencing growth, such as metabolite diffusion into the medium or aeration. CF stimulated cell multiplication of diluted cell suspensions without an evident effect on cell enlargement (Table 3). 

The major factor influencing the rate of mycelial growth is temperature. For every species there... 

Two main factors influence the rate of crystallization at any given temperature (1) the rate of nucleation and (2) the subsequent rate of growth of these nuclei to... 

Hydrolysis and Polycondensation. As shown in Figure 1, at gel time (step C), events related to the growth of polymeric chains and interaction between coUoids slow down considerably and the stmcture of the material is frozen. Post-gelation treatments, ie, steps D—G (aging, drying, stabilization, and densification), alter the stmcture of the original gel but the resultant stmctures aU depend on the initial stmcture. Relative rates, of hydrolysis, (eq. 2), and condensation, (eq. 3), determine the stmcture of the gel. Many factors influence the kinetics of hydrolysis and... 

The rate of cell growth is influenced by temperature, pH, composition of medium, rate of air supply, and other factors. In the case that all other conditions are kept constant, the specific growth rate may be affected by the concentration of a certain specific substrate (the limiting substrate). The simplest empirical expression for the effect ofthe substrate concentration on the specific growth rate is the following Monod equation, which is similar in form to the Michaelis-Menten equation for enzyme reactions ... 

This study showed that the overall crystallization processes for mor-denite, zeolite X, and zeolite A were similar. However, the physical properties of the crystallizing system determine the rate-limiting step for a particular zeolite synthesis. In the case of mordenite in which both the viscosity of the batch composition and the morphology of seed crystals were varied, it was observed that diffusion in the liquid phase was the ratedetermining step. For zeolite X the actual growth rate on the crystal-liquid interface was the rate-limiting factor as shown by identical conversion rates for the seeded and unseeded systems. For zeolite A in the system chosen, both processes influenced the conversion rate. 

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