Explosion fume hood protection

Caution. Tetrahydrofuran is extremely flammable and forms explosive peroxides only freshly distilled, peroxide-free material should be used. Lithium-dispersion is a hazardous material and must be handled in dry conditions and under an inert gas atmosphere. Trimethylchlorosilane and trichloromethylsilane can cause severe skin and eye burns. All manipulations should be carried out in a well-ventilated fume hood protective gloves and safety glasses should be worn. 

CAUTION Thiophenol (atenoh/f) and sulfupyl ohtoznde are highly toxic. Steps A and B should be carried out in an efficient fume hood ahile wearing gloves and adequate eye protection. Sodium nitromethylate is explosive when dry and should be handled only as a slurry. 

Caution Diazomethane shouid be handled in an efficient fume hood behind a protection shield because of its toxicity and the possibility of explosions. 

Caution The reaction should be run behind a shield in a fume hood for protection in ease of explosion. Pressure will build up in the tube einoe 1,1-dimethoxyethylene boils at 89°C and aarbon dioxide is formed. 

Lactic acid is caustic in concentrated form and can cause burns on contact with the skin and eyes. It is harmful if swallowed, inhaled, or absorbed through the skin. Observe precautions appropriate to the circumstances and quantity of material handled. Eye protection, rubber gloves, and respirator are recommended. It is advisable to handle the compound in a chemical fume hood and to avoid repeated or prolonged exposure. Spillages should be diluted with copious quantities of water. In case of excessive inhalation, remove the patient to a well-ventilated environment and seek medical attention. Lactic acid presents no fire or explosion hazard but emits acrid smoke and fumes when heated to decomposition. 

I Caution. Perchlorate salts of complexes can be explosive and should be handled with care in a fume hood and behind a protective shield. They should not be heated as solids or as concentrated solutions. 

Work with systems using fluorine should always be done within a fume hood. The research worker should be protected by an explosive shield. The worker should also wear protective goggles and a face mask. Unless the cylinder valve is operated through a remote control device, the user should wear sturdy gloves with extended cuffs to protect his hands and arms while manipulating the valve. A protective apron should be worn as well. However, aU of these may give only limited protection in the event of an accident since fluorine may react with many common items of persormel protective gear. 

In the event of a leak, remove aU ignition sources and ventilate the area of the leak. Respiratory protection and protective clothing may be necessary in the event of a large spill or release in a confined area. If a cylinder is the source of the leak and the leak cannot be stopped, if possible remove the leaking cylinder to a fume hood or a safe place in the open air, and repair the leak or allow the cyhnder to empty. If the leak has resulted in a fire, water spray can be used to cool the container and to reduce corrosive vapors, keeping in mind that if flames are extinguished, explosive reignition can occur. 

Acid digestion in open vessels is one of the oldest techniques used for mineralization of solid samples. It is a relatively simple—requiring only the use of a hot plate in terms of equipment—but time- and resources-consuming technique. It needs to be carried out in specially designated fume hoods and requires constant attention (full protective equipment as well as protective shields required), due to the potentially violent character of the reactions. Extra care and precaution need to be taken if formation of explosive mixtures (for example, when working with perchloric add) may be possible. 

Chemists, rather generally, operate on the mistaken premise that a fume hood represents the ultimate and universal protection of the chemist against most hazards, be they fire, explosions, or toxic fumes. The validity of this assumption is arguable however, no attention has been paid to the fate of the exhausting fumes, effluent liquids, paper towels, and other residues. Naitov [6] mentions that two deaths from angiosarcoma took place a few miles from a PVC processing operation. We presume that these deaths... 

Sensitive explosive azides can be also easily ignited by electrostatic discharge (ESD). Therefore, wear ESD protective clothing (or at least cotton clothes) and antistatic shoes. The laboratory floor should be ESD conductive or there should be at least static dissipative mats (ESD mats) installed in front of the fume hood where the azides will be synthesized and handled. 

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