Ethylenediamine tetraacetic acid EDTA

Ethylenediamine tetraacetic acid (EDTA) [60-00-4] (Sequestrene), an anticoagulent at 1 mg of the disodium salt per mL blood, complexes with and removes calcium, Ca ", from the blood. Oxalate, citrate, and fluoride ions form insoluble salts with Ca " and chelate calcium from the blood. Salts containing these anticoagulants include lithium oxalate [553-91-3] 1 mg/mL blood sodium oxalate [62-76-0]2 mg/mL blood ... 

Organic compound (such as ethylenediamine-tetraacetic acid (EDTA) or nitrilo-triacetic acid (NTA) having the ability to take metal ions in water and produce soluble, coordinate-bond complexes. Chelants are commonly used in BW deposit control treatments and various cleaning formulations. 

In a separate study, Igwe and Abia46 determined the equilibrium adsorption isotherms of Cd(II), Pb(II), and Zn(II) ions and detoxification of wastewater using unmodified and ethylenediamine tetraacetic acid (EDTA)-modified maize husks as a biosorbent. This study established that maize husks are excellent adsorbents for the removal of these metal ions, with the amount of metal ions adsorbed increasing as the initial concentrations increased. The study further established that EDTA modification of maize husks enhances the adsorption capacity of maize husks, which is attributed to the chelating ability of EDTA. Therefore, this study demonstrates that maize husks, which are generally considered as biomass waste, may be used as adsorbents for heavy metal removal from wastewater streams from various industries and would therefore find application in various parts of the world where development is closely tied to affordable cost as well as environmental cleanliness.46... 

Chiu prepared monodisperse crystalline particles of metal sulfides, such as lead sulfide (PbS cubes 100 A) (I), cupric sulfide (CuS hexagonal bipyramids 200 A) (2), and zinc sulfide (ZnS multifaceted spheres 0.1-0.4 p,m) (3) by introducing hydrogen sulfide gas into dilute acidic solutions of the ethylenediamine tetraacetic acid (EDTA) complexes of the corresponding metal ions (10 4-10-1 mol dm-3) for several minutes at room temperature. 

It is also important to note that the coagulation mechanism in vivo does not occur in solution, but is localized to activated cell surfaces expressing anionic phospholipids such as phosphatidylserine, and is mediated by Ca2+ bridging between the anionic phospholipids and 7-carboxyglutamic acid residues of the clotting factors. This is the basis for using calcium chelators such as ethylenediamine tetraacetic acid (EDTA) or citrate to prevent blood from clotting in a test tube. 

Chromium [10,39], niobium [42], titanium [13], and 90% titanium/10% tungsten [58] have been used as adhesion layers for platinum deposition. Chemical etching procedures based on H202/ethylenediamine tetraacetic acid (EDTA)/ NH4OH have been described for removal of interfering titanium [13] or tita-nium/tungsten [58] adhesion components from the surface of platinum electrodes. The procedure was shown to be effective for more than 24 h after treatment,... 

Crude Cellulases. The culture filtrate obtained from four-day-old cultures was concentrated by lyophilization. The protease inhibitors, phenyl methyl sulfonyl fluoride (PMSF, 2.3mM) and ethylenediamine-tetraacetic acid (EDTA, 0.2mM) were added to the culture solution and the salt concentration was adjusted to 0.5M with NaCl. After stirring at 4°C for at least 30 min to release cellulases from any enzyme-substrate complex which might have formed, the culture solution was centrifuged... 

Ethylenediamine tetraacetic acid (EDTA) was introduced originally as a water-softener and as a textile dyeing assistant because of its ability to form very stable, water soluble complexes with many metal ions, including calcium and magnesium. The equilibria involved in chelation of metal ions by EDTA and related ligands have been exhaustively studied, notably by G. Schwarzenbach and his colleagues, and provide the basis for complexometric methods of chemical analysis. EDTA and its metal complexes have also become probably the most familiar examples of agents used in chelation therapy. 

Tiypsin-ethylenediamine tetraacetic acid (EDTA) in Hank s balanced salt solution, without calcium or magnesium (Invitrogen, Carlsbad, CA). 

The competition between Cu and Ca for ethylenediamine tetraacetic acid (EDTA) and humic acid is an example of a double-exchange reaction (Table 9.4 Hering and Morel, 1989). If Cu is added to a solution of Ca EDTA and Ca humate, it replaces Ca in the weakly bound Ca humate initially, but, as time progresses, it is able to exchange with EDTA-bound Ca by either a ligand- or... 

Hydrogenase, HyD, includes a Fe-S cluster as active site. Photogenerated N,A -dimethyl-4,4 -bipyridinium radical cation, MV+, mediates H2-evolution in the presence of HyD [201-203], see Fig. 40. Different photosensitizers such as Ru(bpy) +, Zn-TMePyP4+ or acridine orange and sacrificial electron donor, i.e. ethylenediamine tetraacetic acid, EDTA, mercaptoethanol or cysteine, have been... 

Results of an in vitro experiment in this study indicated that the midsection had greater uptake than the duodenum or ileum and that oxalate significantly (p<0.05) increased, while phytate significantly (p<0.05) decreased the transport of chromium(III) across all three sections, paralleling the in vivo results. Ethylenediamine tetraacetic acid (EDTA) and citrate were also tested in the in vitro system, but were found to have no effect on chromium(III) intestinal transport therefore, these chelating agents were not tested in vivo (Chen et al. 1973). 

During the Second World War there was a need to treat workers who had been exposed to lead in the paint, particularly white lead or lead(II) carbonate, used on military vehicles and ships. This was achieved with the well known chelating agent ethylenediamine tetraacetic acid (EDTA). Since then other chelating agents have been identified or synthesized for the purpose of binding specific metals. 

Trypsin-ethylenediamine tetraacetic acid (EDTA) 0.05% trypsin with 0.35 mM EDTA-4Na 1 x (Gibco) or pronase powder (Sigma-Aldrich). 

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