Ethyl piperonylate

For tissue analysis, the sample is extracted with ethyl acetate in the presence of sodium chloride and piperonyl butoxide. After centrifugation, the supernatant is evaporated to dryness, and the residue is dissolved with dichloromethane/ hexane (1 1) to be applied onto a Bond-Elut silica cartridge. Following successive cartridge washing with petroleum ether and ethyl acetate/hexane (4 6), chloramphenicol is eluted with ethyl acetate/hexane (7 3) and the eluate is evaporated to dryness. The residue is dissolved in 0.05 M Tris/hydrochloric acid buffer pH 10.4, extracted with diethyl ether, and the extract is evaporated to dryness. Tlie... 

Typical procedure for the cleavage of sulfonate Piperonyl-toluenesulfonate la (2.92 g, 10 mmol) and 37% KF on A1203 (3 weight equivalents of sulfonate) were admixed in a Pyrex test tube and subjected to microwave irradiation for 3 min. After cooling down to room temperature, the solid mass was extracted with ethyl acetate and concentrated in vacuo. The crude product was subsequently purified by column chromatography on silica gel (100-200 mesh, ethyl acetate-hexane, 2 8) to afford sesmol 2a (1.22 g, 88% yield) as white solid. 

Another example of applications concerning separation of piperonylic, 5-, 2-, and 6-methoxypiperonylic acids was performed on silica gel layers using ethyl acetate-hexane-acetic acid (50 50 0.5, v/v) as the mobile phase. Detection was performed by spraying with a chromotropic-sulfuric acid reagent. With these conditions the following hRf values of 64, 54, 47, and 37 were obtained, respectively. 

Philpoi, R.M, and Hodgson, E. (1971). A cytochrome P-450-piperonyl buloxide spectrum similar to that produced by ethyl isocyanide. Life ci. 10,503-512-... 

Methylimidazol-4-yl) methyl] thio] ethyl] amino]-5-piperonyl-4-(lH)-pyrimidinone dihydrochloride ... 

Benzodioxol-5-yl) ethyl octyl sulfoxide. See Piperonyl sulfoxide 1 -[5-(1,3-Benzodioxol-5-yl)-1 -oxo-2,4-pentadienyl] piperidine (E,E)- 1,3-Benzodioxol-5-yl-oxo-2,4-pentadienyl piperine 5-Benzo [1,3] dioxol-5-yl-1-piperidin-1-yl-penta-2,4-dien-1-one. See Piperine... 

Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol. See Levomenol 6-Methyl-2-(4-methyl-3-cyclohexen-1-yl)-5-hepten-2-ol. See Bisabolol a-Methyl-3,4-(methylenedioxy) phenethyl octyl sulfoxide 1-Methyl-2-(3,4-methylenedioxyphenyl) ethyl octyl sulfoxide. See Piperonyl sulfoxide 4-(5-Methyl-1 -methylene-4-hexenyl)-1 -(4-methylpent-3-enyl) cyclohexene. See a-Camphorene... 

Myrcenyl acetate Phenoxyethyl propionate Piperonyl acetone Prenyl benzoate fragrance, deodorants Acetaldehyde ethyl hexyl acetal , 1,2-Dihydrolinalool 4,8-Dimethyl-4,9-decadienal fragrance, detegents Acetaldehyde ethyl phenethyl acetal ... 

Acetaldehyde ethyl phenethyl acetal p-Anisic acid 4-Carvomenthenol trans-Cinnamonitrile Citronellyloxy acetaldehyde Cyclohexyl phenethyl ether 9-Decenol 9-Decenyl acetate Decyl methyl ether Dihydrogeranylacetone Dihydromyrcenyl acetate Dimethyl benzenebutanol Dimethylcyclohexyl methyl ketone 4,8-Dimethyl-4,9-decadienal 5,9-Dimethyl-4,8-decadienal 1,3-Dimethyl-3-phenylbutylacetate Ethyl o-anisate Ethyl maltol Hydroxymethylheptyl methyl ketone Isocyclocitral Maltol Myrcenol Myrcenyl acetate Orange (Citrus aurantium dulcis) peel wax Phenoxyethyl propionate Piperonyl acetone Prenyl benzoate 3,5,5-Trimethylhexyl acetate fragrance, shaving creams Fir (Abies sibirica) needle oil... 

Fig. 1 Photograph taken with a videodensitometer of a Whatman Multi-K SC5 plate showing the 2-D separation of a 16-component mixture of pesticides. The fluorescence-quenched zones are outlined for clarity. Direction 1 ethyl acetate-diisopropyl ether (2.5 97.5) mobile phase on the 20 cm x 3 cm K5F silica gel strip (normal phase TLC) direction 2 acetonitrile-water (85 15) on the adjacent 20 cm x 17 cm C-18F bonded silica gel layer (RPTLC). X Origin. Pesticides 1, propaquizafop 2, quizalofop-P 3, triadimefon 4, triadimenol 5, fenoxycarb 6, quinoxyfen 7, cyromazine 8, oxyfluorfen 9, fluoroglycofen 10, acetochlor 11, metazachlor 12, piperonyl butoxide 13, fur-alaxyl 14, pyriproxyfen 15, buprofezin 16, clofentezine. Source From Separation of a mixture of pesticides by 2D-TLC on two-adsorbentlayer Multi-K SC5 plate, in J. Liq. Chromatogr. Relat. Technol. with permission of Marcel Dekker, Inc.

Amines also react with P-keto-esters to give the corresponding amino acid derivative. When 1.133 was treated with ethylamine in reaction 4, ethyl 3-(N-ethyl-amino)-3-phenylprop-2-enoate (1.134) was obtained. Several other 3-aryl derivatives (piperonyl, p-bromophenyl, p-methylphenyl, and p-nitrophenyl) were prepared by this method. The use of different amines (methylamine, isopropylamine, benzyl-amine, allylamine, aniline) led to several different N-substituted derivatives. ... 

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