Estimation of Epidermal Growth Factor Receptor Expression

Estimation of Epidermal Growth Factor Receptor Expression [Pg.12]

Two scoring systems were proposed for the semi-quantitative evaluation of EGFR overexpression in order to estimate the response of related tumors to the specific immunotherapy [Pg.13]

According to this scoring system tumors having a score of less than 4 considered to have low EGFR expression and show a poor response for the specific therapy. The presence of cells shovfing cytoplasmic stain must also be mentioned. [Pg.13]

Other similar pharmacopathologic diagnostic systems are now developed for other growth factor receptors, which can be the target for immunotherapy agents or specific [Pg.13]

The platelet-derived growth factor receptor is a further growth factor receptor, which binds to the platelet-derived growth factor causing the proliferation of mesenchymal cells. PDGFR is also the target of specific therapeutic antibodies. [Pg.14]

Big Chemical Encyclopedia