Erythrocyte Lipids

Kuriki, K., Tajima, K., and Tokudome, S., Accelerated solvent extraction for quantitative measurement of fatty acids in plasma and erythrocytes. Lipids, 41, 605, 2006. 

Duthie, G.G., Robertson, J.D., Maughan, RJ. and Mortice, P.C. (1990). Blood antioxidant status and erythrocyte lipid peroxidation following distance running. Arch. Biochem. Biophys. 282, 73-83. 

In 1977, Kellogg and Fridovich [28] showed that superoxide produced by the XO-acetaldehyde system initiated the oxidation of liposomes and hemolysis of erythrocytes. Lipid peroxidation was inhibited by SOD and catalase but not the hydroxyl radical scavenger mannitol. Gutteridge et al. [29] showed that the superoxide-generating system (aldehyde-XO) oxidized lipid micelles and decomposed deoxyribose. Superoxide and iron ions are apparently involved in the NADPH-dependent lipid peroxidation in human placental mitochondria [30], Ohyashiki and Nunomura [31] have found that the ferric ion-dependent lipid peroxidation of phospholipid liposomes was enhanced under acidic conditions (from pH 7.4 to 5.5). This reaction was inhibited by SOD, catalase, and hydroxyl radical scavengers. Ohyashiki and Nunomura suggested that superoxide, hydrogen peroxide, and hydroxyl radicals participate in the initiation of liposome oxidation. It has also been shown [32] that SOD inhibited the chain oxidation of methyl linoleate (but not methyl oleate) in phosphate buffer. 

G7. Gjone, E., and Norum, K. R., Plasma lecithin-cholesterol acyltransferase and erythrocyte lipids in liver disease. Acta Med. Scand. 187, 153-161 (1970). 

Ul. Uzel, N., Sivas, A., Uysal, M., and Oz, H. Erythrocyte lipid peroxidation and glutathione peroxidase activities in patients with diabetes mellitus. Harm. Metab. Res. 19, 89—90 (1987). 

Berbamine was isolated from an extract of Berberis poiretii via bioassay-guided techniques using the 3H-diltiazem receptor binding assay. The alkaloid was found to possess calcium channel blocking activities (IC80 3 x 1CT6 M) and to act as an antiperoxidant as measured by the erythrocyte lipid peroxidation test. These data may provide information about the antimyocardial ischemic and antiarrhythmic effects of the berbamine [203]. 

On balance, the evidence points to rhoptry lipids being involved, at the least, in sequestering proteins which, upon introduction into the erythrocyte membrane with or without rhoptry lipids, are directly responsible for the destabilization of the erythrocyte membrane, and subsequent parasitophorous vacuole membrane formation. Whether rhoptry lipids actually become an integral part of the parasitophorous vacuole membrane, wholly or in combination with erythrocyte lipids, is not clear. Rhoptry lipids probably combine directly with erythrocyte lipids in the parasitophorous vacuole membrane. 

Kolanjiappan, K., Manoharan, S., and Kayalvizhi, M., Measurement of erythrocyte lipids, lipid peroxidation, antioxidants and osmotic fragility in cervical cancer patients, Clin. Chim. Acta, 326,143,2002. 

Table 7.3. Total Erythrocyte Lipid of Various Common Mammals (Nelson, 1967)...

Fig. 2. Effect of dietary lipid on linoleic acid content (%) of erythrocyte lipids. At zero day half of the subjects who had received 60 gm of corn oil for three years were fed 60 gm of coconut oil instead (0). A = Corn oil continued X = hospital diet ad libitum.

Smolen JE and Shohet SB Permeability changes induced ty peroxidation in liposomes prepared from human erythrocyte lipids. J Up Ro6 15 273-280, 1974. 

Fig. 3. Scattergram of the correlation between the values of n (Hill coefficient) and the ratio double bond index per saturated fatty acids from membrane erythrocytes lipid. The equation of the regression line and overall correlation coefficient r with its significance are included A, (Na+, K+)-ATPase B, acetylcholinesterase C, (Mg2+)-ATPase D, (Ca2+, Mg2+)-ATPase. Diet supplements a, hydrogenated fat b, lard c, linseed oil d, olive oil e, fat-free f, corn oil and g, standard diet. (Adapted from Bloj et al., 1973a and Galo et al., 1975).

Lyles, D. S., and Landsberger, F. R., 1977, Sendai virus-induced hemolysis Reduction in heterogeneity of erythrocyte lipid bilayer fluidity, Proc. Natl. Acad. Sci. USA 74 1918. 

Staining Applications Bacteria cells cytochrome c oxidase-reconstituted proteoliposomes " fungus sperms epithelial cells erythrocytes lipid bilayer lipid membranes lipid particles liposome lymphocytes lysosomes microorganisms " mitochondrial neuroblastoma cells neutrophils red blood cells tumor cells yeast ... 

A comparison of blood platelet and erythrocyte lipids in man in three age groups from three regions Milan, Cincinnati, and Sicily. 

Stangl, G. I., F. J. Schwarz and M. Kirchgessner, 1999. Moderate long-term cobalt-deficiency affects liver, brain and erythrocyte lipids and lipoproteins of cattle. Nutr. Res. 19, 415-427. 

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