Enzymes of protein

Wergedal, J. E. Enzymes of protein and phosphate catabolism in rat bone. Enzyme property in normal rat. Calc. Tiss. Res. 3, 55 (1969)... 

Several plants are able, for instance, to accumulate toxic nonprotein amino acids which interact with the enzymes of protein biosynthesis (D 9.1). 

Interrupts sulfhydryl enzymes of protein synthesis in die cerebral coit and possibly, die cerebellum causes fibririoiddegerierationcrf m ial layer of cereal... 

Mercury Iraerrupls suKhydryl enzymes of protein syntf sis in the oerdwal cortoc, and po Uy, the cerebellum causes fRjrinoid d eneralion of medial layer of r rebial artoies Cerd>ellar si ts may be prominenl, but are usually associated witii other severe CMS changes ee also T 7-3)... 

Most reactions in cells are carried out by enzymes [1], In many instances the rates of enzyme-catalysed reactions are enhanced by a factor of a million. A significantly large fraction of all known enzymes are proteins which are made from twenty naturally occurring amino acids. The amino acids are linked by peptide bonds to fonn polypeptide chains. The primary sequence of a protein specifies the linear order in which the amino acids are linked. To carry out the catalytic activity the linear sequence has to fold to a well defined tliree-dimensional (3D) stmcture. In cells only a relatively small fraction of proteins require assistance from chaperones (helper proteins) [2]. Even in the complicated cellular environment most proteins fold spontaneously upon synthesis. The detennination of the 3D folded stmcture from the one-dimensional primary sequence is the most popular protein folding problem. 

Averbukh I Sh, Blumenfeld L A, Kovarsky V A and Perelman N F 1986 A model of the mechanism of enzyme action in terms of protein conformational relaxation Blochim. Blophys. Acta. 873 290-6... 

The above method, due to Sorensen, is of great importance in following the course of hydrolysis of proteins by enzymes (p. 516). For example, if the protein and its hydrolysis are represented thus ... 

Enzymes are proteins of high molecular weight, several of which have been isolated in a pure State consequently their precise nature is in some instances still obscure. They form solutions in water and in dilute salt solutions, and are precipitated when such solutions are saturated with ammonium sulphate. 

The most striking thing about proteins is the diversity of their roles m living sys terns siUc is a protein skin and hair are mostly proteins many hormones are proteins a protein carries oxygen from the lungs to the tissues where it is stored by another pro tern and all enzymes are proteins... 

Chymotrypsin (Section 27 10) A digestive enzyme that cat alyzes the hydrolysis of proteins Chymotrypsin selectively catalyzes the cleavage of the peptide bond between the car boxyl group of phenylalanine tyrosine or tryptophan and some other ammo acid... 

Bio-Rex 70 2.4 0.70 Weakly acidic cation exchanger with car-boxylate groups on a macroreticular acrylic matrix for separation and fractionation of proteins, peptides, enzymes, and amines, particularly high molecular weight solutes. Does not denature proteins as do styrene-based resins. 

Metabolic Functions. The functions of the thyroid hormones and thus of iodine are control of energy transductions (121). These hormones increase oxygen consumption and basal metaboHc rate by accelerating reactions in nearly all cells of the body. A part of this effect is attributed to increase in activity of many enzymes. Additionally, protein synthesis is affected by the thyroid hormones (121,122). 

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