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Energies model proteins conversion

Designed elastic model proteins exhibit diverse Junctions that mimic biological functions by diverse means of controlling association of oillike domains. As a result, five experimentally derived axioms phenomenologically categorize means by which energy conversions occur through control of association of oil-like domains. [Pg.5]

A diverse set of energy conversions that sustain life can be experimentally demonstrated by de novo design of elastic-contractile model proteins under the precept of a single, pervasive, mechanism, that is, by a consilient mechanism that creates a common groundwork of explanation. It is a mechanism that achieves function by controlling association of... [Pg.5]

Figure 1.7. Shown are the first reported data of the conversion by an elastic-contractile model protein of chemical energy due to an increase in concentration of acid into the mechanical work of contraction. A Length changes at constant force (isotonic contraction) in phosphate-buffered saline. B Force changes at constant length (isometric contraction) in phosphate-buffered saline. (Reproduced from Urry et al. )... Figure 1.7. Shown are the first reported data of the conversion by an elastic-contractile model protein of chemical energy due to an increase in concentration of acid into the mechanical work of contraction. A Length changes at constant force (isotonic contraction) in phosphate-buffered saline. B Force changes at constant length (isometric contraction) in phosphate-buffered saline. (Reproduced from Urry et al. )...
Step One for Energy Conversion in Mitochondria as Interpreted from Model Protein Studies... [Pg.16]

These results of 18 years ago, demonstrating the capacity of de wovo-designed model protein-based machines for the conversion of chemical energy into mechanical work, remain unex-... [Pg.27]

Figure 2.4. The lefthand side shows a representative sheet of y-irradiation cross-linked elastic-contractile model protein, designed for the conversion of an input energy into the output of pumping iron, per-... Figure 2.4. The lefthand side shows a representative sheet of y-irradiation cross-linked elastic-contractile model protein, designed for the conversion of an input energy into the output of pumping iron, per-...
These experimental demonstrations of our capacity to design model proteins that perform key biological energy conversions constitute our access to the question o/What Sustains Life. [Pg.34]

Figure 2.6. In general, the conversion from the extended state to the contracted state shown in Figure 2.5 is graphed here as a systematic family of sigmoid-shaped curves with a common dependence of oil-like character of the elastic-contractile model protein whether the energy input is thermal, chemi-... Figure 2.6. In general, the conversion from the extended state to the contracted state shown in Figure 2.5 is graphed here as a systematic family of sigmoid-shaped curves with a common dependence of oil-like character of the elastic-contractile model protein whether the energy input is thermal, chemi-...
Synthetic Model Protein Machines Emulate Energy Conversions of Photosynthesis, Respiration, and Motion... [Pg.48]

Ec(uivalence of Energy Conversion to Biology s Proteins yet Structural Limitations of Elastic-contractile Model Proteins... [Pg.50]

The essential aspect of the capacity of the inverse temperature transition to achieve diverse energy conversions resides within large chain molecules, which were just becoming known when the first edition of Schrodinger s book appeared. As we have sketched above, the functional properties of the model protein-... [Pg.59]

Relationship Between Width of Transition Zone (Plotted Using the Log Scale), Efficiency of Energy Conversion, Energy Required for Biological Production of the Model Proteins, and Evolution of More Efficient Machines... [Pg.153]


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