Endothelial cells roles

Oviedo P, Hermenegildo C, Tartn JJ, Cano A (2005) Raloxifene promotes prostacyclin release in human endothelial cells role of COX-1 and COX-2. Fertil Steril 83 1822-1829... 

Li, D., Yang, B., and Mehta, J.L., 1998a, OxLDL induces apoptosis in human coronary endothelial cells role of PKC, PTK, bcl-2, and Fas, Am. J. Physiol. 275 H568-576. 

Choi, J.S., Choi, Y.J., Park, S.H., Kang, J.S., and Kang, Y.H., Flavones mitigate tumor necrosis factor-a-induced adhesion molecule upregulation in cultured human endothelial cells role of nuclear factor-KB, J. Nutr., 134, 1013, 2004. 

Angeli, V., Faveeuw, C., Delerive, P., Fontaine, J., Barriera, Y., Franchimont, N., Staels, B., Capron, M. and Trottein, F. (2001) Schistosoma mansoni induces the synthesis of IF-6 in pulmonary microvascular endothelial cells role of IF-6 in the control of lung eosinophilia during infection. European Journal of Immunology 31,2751-2761. 

Dong F, Zhang X, Wold LE, Ren Q, Zhang Z, Ren J. 2005. Endothelin-1 enhances oxidative stress, cell proliferation and reduces apoptosis in human umbilical vein endothelial cells role of ETB receptor, NADPH oxidase and caveolin-1. Br J Pharmacol 145 323-333. 

Suttorp N, SeegerW, Dewein E et al. (1985) Staphylococcal alpha-toxin-induced PG12 production in endothelial cells role of calcium. In Am J Physiol 248 C127-C135. 

Salcedo, R., Wasserman, K., Young, H. A., Grimm, M. C., Howard, O. M. Z., Anver, M. R., Kleinman, H. K., Murphy, W. J., and Oppenheim, J. J. (1999). Vascular endothelial growth factor and basic fibroblast growth factor induce expression of CXCR4 on human endothelial cells role of SDF-la in angiogenesis. Am. J. Pathol. 154,1125-1135. 

Kevil CG, Okayama N, Trocha SD, et al. Expression of zonula occludens and adherens junctional proteins in human venous and arterial endothelial cells role of occludin in endothelial solute barriers. Microcirculation 1998 5 197-210. 

Rusnati, M., Urbinati, C. and Presta, M. (1993) Internalization of basic fibroblast growth factor (bFGF) in cultured endothelial cells Role of the low affinity heparin-like bFGF receptors. 7. Cell. Physiol. 154 152-161. 

Dolor, R., L. Hurwitz, Z. Mirza, H. Strauss R. Whorton. 1992. Regulation of extracellular Ca entry in endothelial cells role of intracellular calcium pool. J. Am. Physiol 262 C171-C181. 

Chu Y, Piper R, Richardson S, Watanabe Y, Patel P, Heistad DD. Endocytosis of extracellular superoxide dismutase into endothelial cells role of the heparin-binding domain. Arterioscler Thromb Vase Biol 2006 26 1985-1990. 

Lugering N, Kuchaizik T, Gockel H, Sorg C, Stoll R, Domschke W Human intestinal epithelial cells down-regulate IL-8 expression in human intestinal microvascular endothelial cells role of transforming growth factor-beta 1 (TGF-betal). Clin Exp Immunol 1998 114 377. 

Kirkland JB. Lipid peroxidation, protein thiol oxidation and DNA damage in hydrogen peroxide-induced injury to endothelial cells Role of activation of poly(ADP-ribose)polymetasc. Biochim Biophys Acta 1991 1092 319-25. 

M45 Screening of Tn library Essential for virus replication in endothelial cells/role in apoptosis Brune et al. 2001... 

Zhang, H., Schmeisser, A., Garhchs, C.D., Plotze, K., Damme, U., Mugge, A., and Daniel, W.G. Angiotensin Il-induced superoxide anion generation in human vascular endothelial cells Role of membrane-bound NADH-/NADPH-oxidases. Cardip ey. 1999 44(l) 215-22. 

Csiszar A, Smith K, Labinsky N, Orosz Z, Rivera A, Ungvari Z (2006) Resveratrol attenuates TNF-alpha-induced activation of coronary arterial endothelial cells role of NF-kappaB inhibition. Am J Physiol Heart Circ Physiol 291 1694—1699... 

Che W, Lemer-Marmarosh N, Huang Q, et al. Insulin-like growth factor-1 enhances inflammatory responses in endothelial cells role of Gabl and MEKK3 in TNF-alpha-induced c-Jun and NF-kappaB activation and adhesion molecule expression. Circ Res 2002 90 1222-1230. 

Although mast cells and basophils probably account for >90% of stored histamine in the body, histamine is also present in platelets, enterochromaffin-like cells, endothelial cells, and neurons. Histamine can act as a neurotransmitter in the brain. Histaminergic nerves have their cell bodies within a very small area of the brain (the magnocellular nuclei of the posterior hypothalamus) but have axons in most areas of the forebrain. There is also evidence for axons projecting into the spinal (Fig. 1) cord. Finally, there is evidence that histamine synthesis can be induced in tissues undergoing rapid tissue growth and repair. In certain neonatal tissues (e.g. liver), the rate of synthesis of this unstored diffusable histamine (termed nascent histamine) is profound and may point to a role for histamine is cell proliferation. 

The vascular endothelium plays an important role in regulation of vascular tone and permeability. Dilatation of arterioles to increase blood flow and constriction of endothelial cells of postcapillary venules causing exsudation of plasma constituents illustrates the complex nature of this cell type. Moreover, by expression of adhesion molecules and secretion of chemokines endothelial cells play an important role in the recruitment of leukocytes to the inflamed area. Endothelial cells express two basic types of adhesion molecules on their surface ... 

Furchgott RF, Zawadzki JV (1980) Obligatory role of endothelial cells in the relaxation of arterial smooth muscle by acetylcholine. Nature (Lond) 288 373-376... 

OTRs are mainly expressed in myoepithelial cells of the galactiferus channels and the myometrium. The OTRs in vascular endothelial cells, renal epithelial cells (macula densa, proximal tubule) and cardiomyocytes induce the production of NO (vasodilation), natriuresis and release of ANP, respectively. The endometrium, ovary, amnion, testis, epididymis, prostate and thymus also express the OTR supporting a paracrine role of this peptide. Osteoblasts, osteoclasts, pancreatic islets cells, adipocytes, and several types of cancer cells also express OTRs. More over, expression of the OTR... 

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