Enantiomers, liquid chromatographic separation

Masurel, D., Wainer, I.W. (1989). Analytical and preparative high-performance liquid chromatographic separation of the enantiomers of isofamide, cyclophoshamide, and trofosfa-mide and their determination in plasma. J. Chromatogr 490, 133-143. 

Elargitai, T., Kaida, Y., and Okamoto, Y., Preparation and chromatographic evaluation of 3,5-dimethylphenyl carbamoylated beta-cyclodextrin stationary phases for normal-phase high-performance liquid-chromatographic separation of enantiomers, J. Chromatogr., 628, 11, 1993. 

Peter, A., Torok, G., and Armstrong, D.W., High-performance liquid chromatographic separation of enantiomers of unusual amino acids on a teicoplanin chiral stationary phase, J. Chromatogr. A, 793, 283, 1998. 

The evolution of CDs as chiral selectors in the liquid chromatographic separation of enantiomers has been a subject of interest for the last two decades. The presence of the chiral hollow basket, or cavity, makes these molecules suitable for the chiral resolution of a wide range of racemic compounds. At present, the use of CDs as chiral selectors for enantiomeric resolution by liquid... 

Pirkle WH, Finn JM, Hamper BC, Schreiner J, Pribish JR, A useful and conveniently accessible chiral stationary phase for liquid chromatographic separations of enantiomers, in Asymmetric Reactions and Process in Chemistry, Eliels EL, Otsuka S (Eds.), ACS Symposium Series No. 185, American Chemical Society, Washington DC, p. 245 (1982). 

Persson and Andersson [65] reviewed the unusual effects in liquid chromatographic separations of enantiomers on chiral stationary phases with emphasis on polysaccharide phases. On protein phases and Pirkle phases, reversal of the elution order between enantiomers due to... 

Pirkle, W.H. and Pochapsky, T.C. (1989) Considerations of chiral recognition relevant to the liquid chromatographic separation of enantiomers, Chem. Rev. 89, 347-362. 

Tachibana, K. and Ohnishi, A. (2001) Reversed-phase liquid chromatographic separation of enantiomers on polysaccharide type chiral stationary phases, J. Chromatogr. A 906, 127-154. 

Armstrong, D.W., Chiral stationary phases for high performance liquid chromatographic separation of enantiomers a mini-review,./. Liq. Chromatogr., 7, 353, 1984. 

W. H. Pirkle, M. H. Hyun, A. Tsiporas, B. C. Hamper, and B. Banks, A rational approach to the design of highly effective chiral stationary phases for the liquid chromatographic separation of enantiomers, J. Pharm. Biomed. Anal., 2 173 (1984). 

H. Y. Aboul-Enein, S. A. Bakr, M. R. Islam, and R. Rothchild, Direct chiral liquid chromatographic separation of tocainide enantiomers on a crownpak (CR) column and its application to pharmaceutical formulations and biological fluids, J. Liquid Chromatogr., 74 3475(1991). 

Itabashi, Y. and Takagi, T. (1986) High performance liquid chromatographic separation of mono-acylglycerol enantiomers on a chiral stationary phase. Lipids, 21, 413-416. 

Champion, Jr. W.L. Lee, J. Garrison, A.W. DiMarco, J.C. Matabe, A. Prickett, K.B., Liquid chromatographic separation of the enantiomers of tra i-chlordane, cA-chlordane, heptachlor, heptachlor epoxide and a-hexachlorocyclohexane with application to small-scale preparative separation J. Chromatogr. A 1024, 2004, 55-62. 

Imprinted polymers have been used as stationary phase in liquid chromatographic separations and allowed the enantiomer separation for a wide range of compounds [445]. Improved chiral chromatographic resolution faetors have been archived by means of gradient-elution [448]. Imprinted polymer thin films have been tested as selective membranes [450,487], including enantiomer separation [451]. 

S. Allenmark, B. Bomgren, and H. Boren, Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases III. Optical resolution of a series of A-aroyl d, 1-amino acids by high-performance liquid chromatography onbovine serum albumin covalently bound to silica, /. Chromatogr. 264 (1983), 63-68. 

A. M. Rizzi, Band broadening in high-performance liquid chromatographic separations of enantiomers with swollen microcystalline cellulose triacetate packings. 

Allenmark, S. Bomgren, B. Boren, H. Direct liquid chromatographic separation of enantiomers on immobilized protein stationary phases. IV. Molecular interaction forces and retention behaviour in chromatography on bovine serum albumin as a stationary phase. J. Chromatogr. 1984, 316 (12), 617-624. 

Helmchen, G., Nill, G., Flockerzi, D., Schuehle,W.,Youssef, M. S. K. Precision separation of enantiomers by liquid chromatography of diastereomeric derivatives. 4. Extreme liquid chromatographic separation effects by diastereomeric amides with polar substituents, Angew. 

Maier, N. M., Rissanen, K., Lindner,W. Direct high-performance liquid chromatographic separation of peptide enantiomers Study on chiral recognition by systematic evaluation of the influence of structural features of the chiral selectors... 

A Useful and Conveniently Accessible Chiral Stationary Phase for the Liquid Chromatographic Separation of Enantiomers... 

Audebert,R. J. Liq. Chromatogr., Special Issues on Liquid Chromatographic Separation of Enantiomers, Diastereomers, and Configurational Isomers, Marcel Dekker, New York 1979 2, 1063. 

Balmer, K. Persson, A. Lagerstrom, P.-O. Persson, B.-A. Schill, G. Liquid chromatographic separation of the enantiomers of metoprolol and its alpha-hydroxy metabolite on Chiralcel OD for determination in plasma and urine. J.Chromatogr., 1991, 553, 391-397 [plasma urine human dog extracted metabolites fluorescence detection chiral column temp 35 column temp 25 LOD 10 nM]... 

Kelly, J.W. He, L. Stewart, J.T. High-performance liquid chromatographic separation of ondansetron enantiomers in serum using a cellulose-derivatized stationary phase and solid-phase extraction. J.Chromatogr, 1993, 622, 291-295... 

Brocks, D.R. Pasutto, F.M. Jamali, F. Analytical and semi-preparative high-performance liquid chromatographic separation and assay of hydroxychloroquine enantiomers. J. Chromatogr. 1992, 581, 83-92. 

Li, S and WC Purdy (1991). Liquid chromatographic separation of the enantiomers of dinitrophenyl amino acids using a j8-cyclodextrin-bonded stationary phase. Journal of Chromatography, 543,105-112. 

W. H. Pirkle and M. E. Koscho, High Performance Liquid Chromatographic Separation of the Enantiomers ofN-Aryloxazoliniones, N-Aryl Thiazolinones and their Sulfur Derivatives on a Synthetic Chiral Stationary Phase, 7. Chromatogr., 726(1996)91. 

A. Peter, G. Torok and D. W. Armstrong, High-performance Liquid Chromatographic Separation of Enantiomers of Unusual Amino Acids on a Teicoplanin Chiral Stationary Phase, J. Chromatogr. A, 793 (1998)283. 

D.W. Armstrong, W. DeMond, A. Alak, W.L. Hinze, T.E. Riehl and T. Ward, Liquid Chromatographic Separation of Enantiomers Using a Chiral P-Cyclodextrin-Bonded Stationary Phase and Conventional Aqueous-Organic Mobile Phases, Anal. Chem., 57(1985)237. 

D.W. Armstrong, A M. Stalcup, M.L. Hilton, J.D. Duncan, J.R. Faulkner and S.C. Chang, Derivatized Cyclodextrins for Normal-Phase Liquid Chromatographic Separation of Enantiomers, Anal. Chem., 62(1990)1610. 

D.W. Armstrong, C D. Chang and S.H. Lee, (R)- and (S)-Naphthylethyl-carbamate-Substituted P-cyclodextrin Bonded Stationary Phases for the Reversed-Phase Liquid Chromatographic Separation of Enantiomers, J. Chromatogr., 539(1991)83. 

S. Li and W.C. Purdy, Liquid Chromatographic Separation of the Enantiomers of Dinitrophenyl Amino Acids Using a P-Cyclodextrin-bonded Stationary Phase, /. Chromatogr., 543(1991)105. 

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