Emergence, problems

The techniques of continuous improvement are critical in keeping the mentoring program fresh and relevant. Continuous improvement calls for many small enhancements to be made on an almost daily basis, ensuring that emerging problems and inefficiencies are identified and removed before they become ingrained. 

Little is known about the biological effects of APIs on the aquatic environment. The sparse research on this emerging problem reflects, in part, the fact that environmental toxicology has traditionally focused on the effects of acute exposure, rather than on low level, chronic exposure [40, 58]. 

Cecinato A, Balducci C, Nervegna G (2009) Occurrence of cocaine in the air of the World s cities an emerging problem a new tool to investigate the social incidence of drugs Sci Total Environ 407 1683-1690... 

That conscientious psychological support should be given to improve compliance and help patients to cope with emergent problems in living Valproate... 

Sobel JD, Nagappan V, Nyirjesi P (1999) Metronidazole resistant vaginal trichomoniasis— an emerging problem. N Engl J Med 341 292... 

With many large process cooling systems, it is a good idea to have small quantities of certain chemicals available to assist in dealing with process contamination and emergency problems. Such chemicals would include antifoam, mud remover, emulsifier, or demulsifier. 

The extensive IND literature review, evaluating all relevant international publications concerning the drug, should be carefully updated and reanalyzed for trends and emerging problems. This requires more than just an addition to the first IND literature review to reflect the years that have passed the reanalysis of the composite body of literature may reveal hidden problems that should be addressed. 

In this chapter, the different steps in the assessment of mixture exposure are discussed. The chapter starts from emission scenarios and subsequently discusses transformation processes taking place in the environment and their effects on mixture composition. Next, bioavailability is discussed, and exposure scenarios for both humans and biota in the environment are described. These descriptions also consider methods to assess exposure to mixtures. Most data available on mixture exposure are restricted to North America and Europe, but we recognize that there are emerging problems in other regions of the world. We restrict our discussion to man-made chemicals and those natural chemicals subject to regulation (metals, polycyclic aromatic hydrocarbons (PAHs)), because these represent the most well-studied group and the current priorities for risk assessment. 

The Scientific Committees shall draw the Commission s attention to a specific or emerging problem falling within their remit, which they consider may pose an actual or potential risk to consumer safety, public health or the environment by adopting and addressing to the Commission s memoranda or position statements. (European Commission 2009b Ch. 9.10.1)... 

A consistently emerging problem apparently inherent to the use of interferon inducers, even in animal species that do not respond by circulating interferon production, is toxicity. Polycarboxylates owe their toxicity to deposition of the compound in the reticulo-endothelial cells and poor biodegradability. 

Isles A, Maclusky I, Corey M, et al. Pseudomonas cepacia infection in cystic fibrosis An emerging problem. J Pediatr 1984 104 206-210. 

Continue to promote integration amongst the freshwater science community in Europe to maintain research capacity and enable coherent responses to emerging problems. 

Large computer models becoming de facto black boxes is an emerging problem that is not confined to CFD. Within chemical reaction engineering, mistakes can be minimized by always comparing the results to those of simple models and by remembering that experiments are the final proof. 

---