Electrospun nanofiber

Normal transmission IRLD can also be used to characterize polymeric fibers, although scattering can induce sloping baselines. Raman spectroscopy then becomes a convenient alternative. Rutledge et al. have recently probed the orientation in electrospun nanofibers composed of a core of Bombyx mori fibroin and an outer shell of poly (ethylene oxide) [24], The orientation values were low, less than 0.1, as is often the case in electrospun fibers. 

The electrospun nanofiber webs, with very high surface area to volume ratio and high... 

HE. Schreuder-Gibson, P. Gibson, K Seneeal, M Sennett, J. Walker, W. Yeomans, et al. 2002. Protective textile materials based on electrospun nanofibers. Journal of Advanced Materials44-55. 

G. Verreck, I. Chim, J. Rosenblatt, J. Peeters, A.V. Dijck, J. Mensch, M. Noppe, M.E. Brewster. 2003. Incorporation of drugs in an amorphous state into electrospun nanofibers composed of a waterinsoluble, nonbiodegradable polymer. J. Control. Release, 92. pp.349. 

PW. Gibson, HE. Schreuder-Gibson, D. Rivin. 2001. Transport properties of porous membranes based on electrospun nanofibers. Colloids and Surfaces A Physicochemical and Engineering Aspects, 187.pp.469 81. 

Liu,Z. Kang, X. Fang, F. 2010. Solid phase extraction with electrospun nanofibers for determination ofretinolandalpha-tocopherolinplasma.Microchim. Acta. 168 59-64. Mac-Mod., 2011. Mac-Mod Analytical, ProtoSlL C30 reversed phase HPLC columns for the separation of hydrophobic structural isomers, from http //www. bischoff-chrom.com/pdf/BlSCHOFF-Appl-l%20%5BSchreibgesch%FCtzt%5D. pdf. accessed March 26, 2011. 

At present a few studies of nanofibers and nanombes are focused on CNS drug delivery. One study evaluated electrospun nanofibers of a degradable polymer, PLGA, loaded with antiinflammatory agent, dexamethasone, for neural prosthetic applications (Abidian and Martin, 2005). A conducting polymer, poly(3,4-ethylenedioxythiophene), was deposited to the nano-fiber surface and the coated nanofibers were then mounted on the microfabricated neural microelectrodes, which were implanted into brain. The drug was released by electrical stimulation that induced a local dilation of the coat and increased permeability. 

Fig. 34 SEM images of PF8/PMMA blend electrospun nanofibers with a 10 and b 50 wt. % of PF8. Reprinted with permission from [145]. (2007) by the American Chemical Society...

Fig. 4 (a) Photograph of the overall 3D woodpile structure with dimensions of 9 x 9 x 3.5 mm. (b) Hybrid basic unit layer composed of microfibers and the electrospun nanofiber matrix, (c, d) Magnified images of (b) (Adapted from [64])... 

Starch/PCL fiber bonded microscaffolds with electrospun nanofibers... 

Cell attachment and proliferation [64] was improved by the addition of electrospun nanofibers, with the largest increase due to PCL/collagen nanofibers... 

Creating Electrospun Nanofiber-Based Biomimetic Scaffolds for Bone Regeneration... 

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