Electrochemical Recognition of Neutral Guest Species

Molecular mechanics calculations (142) performed on neutral inclusion complexes of cavitand (101) suggested that the cavitand cavity would allow inclusion of small organic guest species such as carbon 

Future work is focused at preparing water-soluble analogs in an effort to utilize the hydrophobic effect (147) as the driving force for inclusion of neutral organic guest species. 

The nature of the solvent can also have a profound effect on the electrochemical recognition process. All of the redox-responsive ligand systems cited in this review give examples of guest cation/anion redox couple perturbations in organic solvents such as dichloromethane and acetonitile. The next challenge will be to demonstrate analogous redox-responsive behavior in the aqueous environment. 

Finally, apart from the obvious future commercial applications of redox-active ligand systems to a new class of amperometric molecular sensing devices, they also promise to exhibit exciting new redox catalytic properties by promoting redox reactions on an included guest substrate, and novel solid-state anisotropic electronic, magnetic, and optical (49) behavior. 

I thank my postgraduate and postdoctoral co-workers for undaunting motivation and determination to succeed in this multidisciplinary research field their names appear in the references. Special thanks go to Dr. M. G. B. Drew for his many structure determinations and molecular mechanics calculations. I gratefully acknowledge the financial support of the SERC, ICI Specialties, ICI Pharmaceuticals, ICI Chemicals and Polymers, BP (Sunbury), MediSense, Ministry of Defence, Kodak, Serpentix, Unilever, The Royal Society, NATO, Research Corporation Trust, and L. and D. Blond. 

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Towards electrochemical recognition of neutral guest species by... 

IV. Electrochemical Recognition of Neutral Guest Species Redox-Active Cavitand Host Molecules... 

The molecular recognition of anionic guest species by positively chaiged or neutral receptors is a relatively new area of research of growing interest in view of the key roles that these anions play in biochemical and chemical processes. For this reason, as part of the electrochemical studies, we decided to examine the use of the redox-active ferrocenyl dendrimers 3 and 4 that contain multiple N-H linkages capable of participating in H-bonding, as well as characteristic internal cavities,... 

Effective charge and transition-state structure in solution, 27, 1 Effective molarities of intramolecular reactions, 17,183 Electrical conduction in organic solids, 16,159 Electrochemical methods, study of reactive intermediates by, 19, 131 Electrochemical recognition of charged and neutral guest species by redox-active receptor molecules, 31, 1... 

Receptor molecules, redox-active, electrochemical recognition of charged and neutral guest species... 

Electrochemical Recognition of Charged and Neutral Guest Species by Redox-active Receptor Moleculesf... 

Beer, P. D. Gale, P. A. Chen. G. Z. Mechanisms of electrochemical recognition of cations, anions and neutral guest species by redox-active receptor molecules, Coord. Chem. Rev. 1999, 185-186, 3-36. 

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