Effect of combination with

The titration of proteins with weak acids is not considered in this review, since in the only detailed study of the subject (Steinhardt, Fugitt, and Harris (1943) on wool keratin) the effect of selective solvation of the fiber by undissociated weak acid was added to the effect of combination with hydrogen ion. 

To involve the staff in a change process, of which the installation or improvement of a ventilation system is one example, is also of vital importance for a successful result. Their knowledge of how the work is or may be done in an effective way, combined with the knowledge of the ventilation expert, increases the chance for an effective and durable solution of an air quality problem. Visualization methods have thereby proved to be effective both to communicate important knowledge and to motivate the staff to take part in the process. ... 

Conventional IRMS requires relatively large sample volumes in a purified gaseous form. Recently, an on-line GC-IRMS system has been developed which combines the high purification effect of GC with the utmost precision of IRMS. Sometimes this system may not be Sufficient to determine characteristic minor components from complex matrices, and therefore MDGC-IRMS systems have been developed for the analysis of complex plant extracts and flavour components (25-27). 

The most recognized toothpaste ingredient is probably the class of compounds known as fluorides. Stannous fluoride was the first to be used in toothpaste because, unlike sodium fluoride, it did not lose its effectiveness when combined with the abrasive most common at the time, calcium phosphate. Later, sodium mono-fluorophosphate came into popular use because it too could be used with the common abrasives. 

In the first chapter, I have discussed the limitations of high performance liquid chromatography (HPLC) and mass spectrometry when used in isolation and how the combination of the two allows these to be overcome. In this chapter, the effect of combining the two techniques with regard to the individual performance characteristics are explored. 

None of the above efforts considered depropagation effects in combination with the optimal reactor problem. When a polymerization is carried out at high temperature to reach a fmal monomer concentration which is low, the thermodynamic (depropagation) effects may become more important than the kinetic ones. 

Effects of Combinations of Chemicals WITH Differing Modes of Action... 

Hj-antagonists alone, such as cimetidine or ranitidine, have a modest effect on cutaneous flush reaction and maybe also on the heart [14, 52]. However, when applied they should be given together with Hj-antagonists. There are some studies showing a beneficial effect of combined H - and Hj-antagonist treatment or pretreatment in anaphylaxis [46, 53]. 

Seitz RJ, Meisel S, Moll M, Wittsack JH, Junghans U, Seibler M. The effect of combined thrombolysis with rtPA and tirofiban on ischemic brain lesions. Neurology 2004 62 2110-2112. 

The a-tocopherol, P-carotene (ATBC) Cancer Prevention study was a randomised-controlled trial that tested the effects of daily doses of either 50 mg (50 lU) vitamin E (all-racemic a-tocopherol acetate), or 20 mg of P-carotene, or both with that of a placebo, in a population of more than 29,000 male smokers for 5-8 years. No reduction in lung cancer or major coronary events was observed with any of the treatments. What was more startling was the unexpected increases in risk of death from lung cancer and ischemic heart disease with P-carotene supplementation (ATBC Cancer Prevention Study Group, 1994). Increases in the risk of both lung cancer and cardiovascular disease mortality were also observed in the P-carotene and Retinol Efficacy Trial (CARET), which tested the effects of combined treatment with 30 mg/d P-carotene and retinyl pahnitate (25,000 lU/d) in 18,000 men and women with a history of cigarette smoking or occupational exposure to asbestos (Hennekens et al, 1996). 

Morita et al. [69] optimized the mobile phase composition using the PRISMA model for rapid and economic determination of synthetic red pigments in cosmetics and medicines. The PRISMA model has been effective in combination with a super modihed simplex method for fadhtating optimization of the mobile phase in high performance thin layer chromatography (HPTLC). 

Corticosteriods are used for their immunosuppressive effect in combination with PEX because they are of no benefit when used alone in this population. The most commonly used agents are methylprednisolone 1 g/day intravenously and prednisone 1 mg/kg per day orally. 

Chiba K, Hoshino Y, Suzuki C, et al. FTY720, a novel immunosuppressant possessing unique mechanisms. I. Prolongation of skin allograft survival and synergistic effect in combination with cyclosporine in rats. Transplant Proc 1996 28(2) 1056-1059. 

Although requirements such as those mentioned may be desirable or even essential for an active plant growth regulator, the mechanism of action of the substance in the cell is still unknown. The suggestion that certain of these active molecules may exercise their effects by combination with important thiol enzymes may be most fruitful. 

Dimers (73) and (74) were formed in approximately equal amounts in all cases, although, as in the cases of 2-cyclopentenone and 2-cyclohexenone, the relative amount of (72) (either cis-syn-cis or cis-anti-cis) was found to vary substantially with solvent polarity. As in 2-cyclopentenone, this increase in the rate of head-to-head dimerization was attributed to stabilization of the increase in dipole moment in going to the transition state leading to (72) in polar solvents. It is thought that the solvent effect in this case is not associated with the state of aggregation since a plot of Stem-Volmer plot and complete quenching with 0.2 M piperylene indicate that the reaction proceeds mainly from the triplet manifold. However, the rates of formation of head-to-head and head-to-tail dimers do not show the same relationship when sensitized by benzophenone as in the direct photolysis. This effect, when combined with different intercepts for head-to-head and head-to-tail dimerizations quenched by piperylene in the Stem-Volmer plot, indicates that two distinct excited triplet states are involved with differing efficiencies of population. The nature of these two triplets has not been disclosed. 

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