Dyspareunia

Patients with IBS may experience comorbidities outside the gastrointestinal tract such as fibromyalgia, sleep disturbances, headaches, dyspareunia, and temporomandibular joint syndrome. 

Phosphodiesterase 5 inhibitors such as sildenafil are effective for MS-induced erectile dysfunction.14 In women, vaginal dryness or dyspareunia may respond to lubricating jellies. 

Therapeutic modalities for amenorrhea are targeted at restoring the normal menstrual cycle. The goals of treatment are to preserve bone density, prevent bone loss, and restore ovulation, thus improving fertility as desired. Amenorrhea resulting from conditions contributing to hypoestrogenism also may affect quality of life via the induction of hot flashes (premature ovarian failure), dyspareunia, and in prepubertal females, lack of secondary sexual characteristics and absence of menarche. 

Dyspareunia may result from vaginal dryness. Water-based lubricants may provide relief for several hours after application. Moisturizers may provide relief for a longer period of time and potentially can prevent infections by maintaining the acidic environment in the vagina. Both these treatments require frequent application. 

UTI dyspareunia, sexual dysfunction, pelvic pain Dysuria, CVA tenderness, frequency... 

Recurrent coughing, urinary incontinence, dyspareunia, vaginal itching, multiple UTIs (-) nocturia, enuresis, urgency, dysuria, frequency, lower abdominal fullness, decreased force of stream... 

Although rare, dyspareunia may occur with vulvovaginal... 

Other symptoms include vaginal dryness, dyspareunia, urogenital atrophy, sleep disturbances, sexual dysfunction, and impaired concentration and memory. 

Abnormal vaginal discharge, vulvar itching/irritation, dysuria, dyspareunia... 

Symptoms May be asymptomatic (more common in males than females) or minimally symptomatic Urethral discharge (clear to mucopurulent) Dysuria, pruritus May be asymptomatic or minimally symptomatic Scant to copious, typically malodorous vaginal discharge (50-75%) and pruritus (worsen during menses) Dysuria, dyspareunia... 

In addition, about 15% of cases of pelvic pain are due to endometriosis, and most primary care physicians consider pelvic pain to be a common clinical problem that accounts for as much as 25% of routine gynecologic office visits (Hurd 1998). Endometriosis is frequently associated with several types of pelvic pain such as dysmenorrhea, chronic pelvic pain, deep dyspareunia, and, occasionally, painful defecation (Hurd 1998). Specifically, endometriosis was... 

Endometriosis is abnormal growth of endometrial tissue in the peritoneal cavity. Women with this disorder have dysmenorrhea, dyspareunia, chronic pelvic pain, and infertility. Danazol (Danocrine) is a 2,3-isoxazol derivative of 17a-ethynyl testosterone (ethisterone) that has weak virilizing and protein anabolic properties. It is effective in endometriosis through its negative feedback... 

For the treatment of vaginal complaints such as dyspareunia, dryness and itching. 

Tamoxifen can cause loss of libido (63). In 57 patients sexual desire, arousal, and the ability to achieve orgasm were unaffected by tamoxifen (64). There was a 54% incidence of dyspareunia, but this seemed to be a consequence of co-administration of chemotherapy, which can cause vaginal dryness and loss of libido, rather than an effect of tamoxifen. 

Corbellis, L., et al. 2004. A danazol-loaded intrauterine device decreases dysmenorrheal, pelvic pain, and dyspareunia associated with endometriosis. Fertil Steril 82 239. 

Endometriosis-associated pain is secondary to structural and/or inflammatory causes. The lesions may cause pain by compression of nerve fibers. Increased pressure within endometriomas (cysts within the ovary) has been linked to dyspareunia. Endometrial lesions also generate local inflammation with prostaglandin release and increase the risk of developing adhesions. Endometrial lesions contain estrogen and progesterone receptors, and symptoms may correlate with the cyclic release of hormones during the menstrual cycle. 

Endometriosis should be suspected in women with subfertility, dysmenorrhea, dyspareunia, or chronic pelvic pain. A definitive diagnosis can be made only by direct surgical visualization of endometrial lesions. Lesions typically are found in the pelvis... 

Use of OCs to treat endometriosis pain is desirable because of the potential for long-term use without significant side effects. A low-dose OC administered cyclically was compared with a GnRH-a in a randomized trial. Both groups showed overall improvement in dyspareunia, nonmenstrual pain, and dysmenorrhea at 6 months. The rate of recurrent symptoms 6 months after cessation of therapy was equal between groups. 

Secondary amenorrhea Vasomotor symptoms (hot flushes and night sweats), sleep disturbances, mood changes, sexual dysfunction, problems with concentration and memory, vaginal dryness, and dyspareunia... 

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