Drug precautions/contraindications

Discuss the uses, general drug action, contraindications, precautions, interactions, and adverse reactions of the fluoroquinolones and aminoglycosides. 

These drug are contraindicated in patients with known hypersensitivity to the individual drug or any component of die preparation. There are no significant precautions or interactions when used as directed. 

Drug Precautions Modules Minimization of potential contraindications between drug use, medical conditions, age (pediatric and geriatric), pregnancy, and lactation. Includes Pediatric Precautions Module, Geriatric Precautions Module, Pregnancy Precautions Module, and Lactation Precautions Module. 

Drugdass MOA Lipid effects Adverse lections Metabolism Drug interactions Contraindications/ precautions... 

PRECAUTIONS AND CONTRAINDICATIONS Melarsoprol should be given to patients only under hospital supervision. The initial dose must be based on clinical assessment rather than body weight. Initiation of therapy during a febrile episode is associated with an increased incidence of reactive encephalopathy. Administration of melarsoprol to leprous patients may precipitate erythema nodosum. The drug is contraindicated during epidemics of influenza. Severe hemolytic reactions have been reported in patients with glucose-6-phosphate dehydrogenase deficiency. 

Identify the uses, general drug actions, and general adverse reactions, contraindications, precautions, and interactions of the penicillins. 

The fluoroquinolones are contraindicated in patients with a history of hypersensitivity to the fluoroquinolones, in children younger than 18 years, and in pregnant women (Pregnancy Category C). These drugs also are contraindicated in patients whose life-styles do not allow for adherence to the precautions regarding photosensitivity. 

Other contraindications and precautions are listed below, according to die specific drug. Numerous interactions are possible widi the antiviral dragp. Only the most significant interactions are listed for selected dra . The nurse should consult an appropriate source for a more extensive listing of interactions. 

Chloroquine is contraindicated in patients with known hypersensitivity. Precautions and interactions for chloroquine are provided in the discussion of the drug in the Antimalatial Dragp section. 

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