FDA pregnancy categories

TABLE 17.1 FDA pregnancy category designations for product labeling... 

Topical cyclosporine is safe and well tolerated in most patients, and there are no absolute contraindications to its use. It has not been approved for use in children, and the FDA pregnancy category is C. 

Pregnant women should not directly care for patients receiving ribavirin aerosol (FDA pregnancy category X). 

Caffeine is in the FDA pregnancy category C and has been shown to cross the placenta and achieve blood and tissue concentrations in the fetus. Excessive intake of caffeine by pregnant women has been associated with fetal arrhythmias. Pregnant women are advised to limit caffeine intake to less than 300 mg (approximately six cups black tea) daily (PDR 2006). 

The compound quinine is listed in FDA pregnancy category C, "Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks."... 

Caution in mental illness history risk of latent psychosis activation or increased risk of suicidality Caution in pregnancy (FDA Pregnancy Category D)... 

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