Drug delivery future developments

Lee, V.H.L. Robinson, J.R. "Review topical ocular drug delivery recent developments and future challenges" Journal of Ocular Pharmacology, 1986,1,67. 

Lee, V.H.L., and J.R. Robinson. 1986. Topical ocular drug delivery Recent developments and future challenges. J Ocul Pharmacol 2 67. 

Ilium L (2012) Nasal drug delivery-recent developments and future prospects. J Control Release 161 254—263... 

In the last few years there have been new creative methods of preparation of novel hydrophilic polymers and hydrogels that may represent the future in drug delivery applications. The focus in these studies has been the development of polymeric structures with precise molecular architectures. Stupp et al. (1997) synthesized self-assembled triblock copolymer, nanostructures that may have very promising applications in controlled drug delivery. Novel biodegradable polymers, such as polyrotaxanes, have been developed that have particularly exciting molecular assemblies for drug delivery (Ooya and Yui, 1997). 

J. J. Yang, H. Ueda, K. Kim, and V. H. Lee. Meeting future challenges in topical ocular drug delivery Development of an air-interfaced primary culture of rabbit conjunctival epithelial cells on a permeable support for drug transport studies. J Control Release 65 1-11 (2000). 

Significant developments have occurred in recent years in the fields of biopolymers and biomaterials. New synthetic materials have been synthesized and tested for a variety of biomedical and related applications from linings for artifical hearts to artifical pancreas devices and from intraocular lenses to drug delivery systems. Of particular interest in the future is the development of intelligent polymers or materials with special functional groups that can be used either for specialty medical applications or as templates or scaffolds for tissue regeneration. 

The aim of this review is to consider the types of medications/drug delivery systems that could be developed for administration in battlefield situations, current systems and possible future developments. It will consider battlefield situations, the medical aid provided, current drug delivery technologies and those employed at the front line, followed by a consideration of some future possible developments. 

Yandamme, T.F. 2002. Microemulsions as ocular drug delivery systems Recent developments and future challenges. Prog Retin Eye Res 21 15. 

The purpose of this overview chapter is to provide perspectives in the current status and future prospects of controlled release drug delivery. This is accomplished by examining various delivery systems from a mechanistic point of view, exploring applications of these systems, and discussing relevant biopharmaceutical parameters. A major section of this book is devoted to fundamental issues and applications of transdermal and transmucosal delivery systems (Chapter 6,8,17-23). Other developing systems of future potential... 

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