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Dorsal striatum

Motor stereotypy Dorsal striatum (i.e., caudate putamen)... [Pg.1042]

QUESTION Is there a parallel to the reticulata component of the striatum, the dorsal striatum in the ventral tegmental area ... [Pg.138]

Giuffrida A, Parsons LH, Kerr TM, Rodriguez de Fonseca F, Navarro M, Piomelli D. Dopamine activation of endogenous cannabinoid signaling in dorsal striatum. Nat Neurosci 1999 2 358-363. [Pg.129]

McQuade Sharp (1997) tested whether electrical stimulation of the DRN or the MRN releases 5-HT in rat forebrain regions in a pattern that correlates with the distribution of 5-HT projections from the serotonergic nuclei. Stimulation of the DRN evoked the release of 5-HT in the frontal cortex, dorsal striatum, globus pallidus, and ventral hippocampus. Conversely, 5-HT release in dialysates collected from the dorsal and ventral hippocampus and the medial septum was increased in response to MRN stimulation. Thus, the functional mapping of DRN... [Pg.247]

Berlanga, M.L., Olsen, C.M., Chen, V. et al. Cholinergic interneurons of the nucleus accumbens and dorsal striatum are activated by the self-administration of cocaine. Neuroscience. 120 1149, 2003. [Pg.35]

Anderson JJ, Chase TN, Engber TM. 1993. Substance P increases release of acetylcholine in the dorsal striatum of freely moving rats. Brain Res 623(2) 189-194. [Pg.243]

Tsukada et al. (2002) 4 Macada mulatto monkeys C-Raclopride PET (B/1) IV nic (B/I) Slight j, BP (indicating f DA concentration) in anesthetized, but not conscious monkeys, in dorsal striatum... [Pg.153]

There is evidence that nicotine also stimulates the DA projections to the dorsal striatum (BenweU and Balfour 1997 Quick 2004). To date, relatively few studies have sought to directly link this response to the drug with behavioural changes associated with dependence. Nevertheless, a number of studies have implicated these projections in the responses to rewarding stimuli, particularly in expectation of reward (Schultz 2006). A failure to deliver an anticipated reinforcer results in transient reduction in the activity of these neurones. Rice and Cragg (2004) have reported that... [Pg.220]

The ventral striatum, like its dorsal counterpart, is part of a system of CSTC loops. Only recently has it become clear that these loops are as segregated and discrete as those in the dorsal striatum. Glutamatergic inputs, which arise from the orbital and medial prefrontal cor-... [Pg.155]

Dickinson SD, Sabeti J, Larson GA, Giardina K, Rubinstein M, Kelly MA, Grandy DK, Low MJ, Gerhardt GA, Zahniser NR (1999) Dopamine D2 receptor-deficient mice exhibit decreased dopamine transporter function but no changes in dopamine release in dorsal striatum. J Neu-rochem 72 148-56... [Pg.327]

Interestingly, DSE/I are not observed at all synapses where presynaptic CB1 receptors are found. For example, in the dorsal striatum EC-dependent DSE is not observed at glutamatergic synapses known to express other forms of EC-dependent plasticity (Gerdeman et al. 2002 Kreitzer and Malenka 2005 Yin et al. 2006). Perhaps postsynaptic activation by depolarization alone is not sufficient to induce EC production or release from the postsynaptic elements of these synapses. [Pg.450]

De Groote L, Olivier B, Westenberg HG. Role of 5-HT1B receptors in the regulation of extracellular serotonin and dopamine in the dorsal striatum of mice. Eur J Pharmacol 2003 476 71-77. [Pg.400]

The so-called clinical effect of neuroleptics, their chemical loboto-mizing impact, is primarily caused by the blockade of dopaminergic nerves, especially the D2 receptors, in the ventral striatum, with their connections to the limbic system and frontal lobes (chapters 1 and 2). However, blockade of the same D2 receptors in the dorsal striatum is the probable cause of extrapyramidal reactions, including TD (Ethier et al., 2004 Seeman, 1995). Hence, as described in chapter 1, the so-called therapeutic effect is inextricably entwined with some of the worst adverse effects. [Pg.55]

Rebec, G., White, I., 8c Puotz, J. (1997). Responses of neurons in dorsal striatum during amphetamine-induced focused stereotypy. Psychopharmacology, 130, 343—341. [Pg.512]

Dopaminergic projections are classically divided in nigrostriatal, mesolimbic, and mesocortical systems. The nigrostriatal system projects from the substantia nigra (SN) to the dorsal striatum, and has been... [Pg.4]

Alcantara AA, Chen V, Herring BE, Mendenhall JM, Berlanga ML. 2003. Localization of dopamine D2 receptors on cholinergic interneurons of the dorsal striatum and nucleus accumbens of the rat. Brain Res 986 22-29. [Pg.30]

As mentioned earlier, the striatum is classically divided into (i) dorsal striatum or neostriatum, which includes most of the caudate and putamen, and (ii) ventral striatum, which includes the NAc, the ventromedial parts of the caudate and putamen, and the striatal portion of the olfactory tubercle. [Pg.45]

A compartmental inhomogeneous organization of neuropeptides, DA and calbindin has been demonstrated in the NAc, but overall the chemoarchitecture and connectivity indicated that the NAc is not organized into patch and matrix compartments equivalent to those in the dorsal striatum, but is instead organized in several compartments with different chemoarchitectural features and different input-output relationships (Voorn et al., 1989). [Pg.53]


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Dorsal

Dorsal striatum (caudate

Striatum

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