Dopamine-transporter inhibitors

Therefore, dopamine transporter inhibitors exhibit less effect in the FC. There, dopamine seems to be reuptaken by the norepinephrine transporter, which dopamine actually has a higher affinity for than norepinephrine itself. 

Hanania, T. and Zahniser, N.R., Locomotor activity induced by noncompetitive NMDA receptor antagonists versus dopamine transporter inhibitors opposite strain differences in inbred long-sleep and short-sleep mice, Alcohol Clin. Exp. Res., 26, 431, 2002. 

Hoffman, B.T., Kopajtic, T., Katz, J.L., and Newman, A.H. 2D QSAR Modeling and preliminary database searching for dopamine transporter inhibitors using genetic algorithm variable selection of Molconn Z descriptors./. Med. Chem. 

Other approaches, some of which are still in clinical development, include restoration of the acetylcholine-dopamine balance in the basal ganglia, neuronal nicotinic receptor agonists, neurotrophic immunophilins, dopamine transport inhibitors, COMT-inhibitors, and adenosine A2A receptor antagonists.162,163 Also surgical therapies are used or under development, including stereotactic thalamotomy, continuous electric thalamus stimulation,164 posteroventral pallidotomy and transplantation of embryonal substantia nigra cells. 

Raitiri, M. Cerrito, F. Cervoni, A.M. and Levi, G. Dopamine can be released by two mechanisms differentially affected by the dopamine transport inhibitor nomifensine. J Pharmacol Exp Ther 208 195-202, 1979. 

K. M. (2000) Discovery of a novel dopamine transporter inhibitor, 4-hydroy-1 -methyl-4-(4-methylphenyl)-3-piperidyl 4-methylphenyl ketone, as a potential cocaine antagonist through 3D-database pharmacophore searching. Molecular modeling. Stracture-activity relationships, and behavioral pharmacological studies. J. Med. Chem. 43 351-360. 

D QSAR Modeling and Preliminary Database Searching for Dopamine Transporter Inhibitors Using Genetic Algorithm Variable Selection of Molconn Z Descriptors. 

Sodium-dependent dopamine transporter inhibitor Neurotoxicity... 

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