DNA microarray applications

Palka-Santini M, Putzfeld S, Cleven BE, Kronke M, Krut O (2007) Rapid identitication, virulence analysis and resistance profiling of Staphylococcus aureus by gene segment-based DNA microarrays application to blood culture post-processing. J Microbiol Methods 68 468 77... 

Lettieri, T., Recent applications of DNA microarray technology to toxicology and ecotoxicology,... 

Leowohl JM et al. Application of DNA microarrays to study human alcoholism. 

Afshari CA et al. Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation. Cancer Res 1999 59 4759-4760. 

Shoida T, /. Environ. Application of DNA microarray to toxicological research, Pathol. Toxicol. Oncol., 23, 13-31, 2004. 

In the following sections, we will look at representative applications of DNA microarrays in the biomedical research field. 

Debouck, C. Goodfellow, P. (1999). DNA microarrays in drug discovery and development. Nature Genet. 21, 48-50. Gabig, M. Wegrzyn, G. (2001). An introduction to DNA chips principles, technology, applications and analysis. Acta Biochim. Polon. 48(3), 615-622. 

One of the early concerns about the application of DNA microarray to toxicology has been how to properly compare experiments that use a wide variety of commercial and proprietary platforms, protocols, and analyses methods. The Health and Environmental Sciences Institute (HESI) of the International Life Sciences Institute (ILSI) has... 

Kramer JA, Pettit SD, Amin RP et al. Overview on the application of transcription profiling using selected nephrotoxicants for toxicology assessment. Environ Health Perspect 2004 112 460-464. Newton RK, Aardema M, Aubrecht J. The utility of DNA microarrays for characterizing genotoxicity. Environ Health Perspect 2004 112 420 22. 

Applications of DNA and Protein Microarray Technology DNA microarray technology can be applied for the following purposes. 

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