Carcinogens identification

Afshari CA et al. Application of complementary DNA microarray technology to carcinogen identification, toxicology, and drug safety evaluation. Cancer Res 1999 59 4759-4760. 

Although every effort is made to prepare the monographs as accurately as possible, mistakes may occur. Readers are requested to communicate any errors to the Unit of Carcinogen Identification and Evaluation, so that corrections can be reported in future volumes. 

Y. Grosse, Unit of Carcinogen Identification and Evaluation J. Korte, Environmental Cancer Epidemiology V. Krutovskikh, Unit of Gene-Environment Interactions... 

D. McGregor, Unit of Carcinogen Identification and Evaluation Responsible Officerf... 

There are three principal ways for a chemical to be added to the Proposition 65 list. A chemical can be listed if either of two independent committees of scientists and health professionals finds that the chemical has been clearly shown to cause cancer or birth defects or other reproductive harm. These two committees are the Carcinogen Identification Committee (CIC) and the Developmental and Reproductive Toxicant (DART) Identification Committee, and both are part of OEHHA s Science Advisory Board. The committee members are appointed by the Governor and are designated as the State s Qualified Experts for evaluating chemicals under Proposition 65. When determining whether a chemical should be placed on the list, the committees base their decisions on the most current scientific information available. OEH-HA staff scientists compile all relevant scientific evidence on various chemicals for the committees to review. The committees also consider comments from the public before making their decisions. 

Herceg Z, Lambert MP, van Veldhoven K, Demetriou C, Vineis P et al (2013) Towards incorporating epigenetic mechanisms into carcinogen identification and evaluation. Carcinogenesis 34(9) 1955-1967... 

Kriek, E., Den Engelse, L., Scherer, E., and Westra, J. G. (1984). Formation of DNA modifications by chemical carcinogens. Identification, localization and quantification. Biochim Biophys Acta 738, 181-201. 

B6. Berenblum, I., Carcinogen Identification and Mechanism of Action, pp. 25-36. Raven Press, New York, 1979. 

Harri Vainio, Unit of Carcinogen Identification and Evaluation, International Agency for Research on Cancer, World Health Organization, 150 Cours Albert Thomas, 69372-Lyon, Cedex 08, France. 

Strauss, B., Altamirano, M., Bose, K., Sklar, R., and Tatsumi, 1979, Carcinogen-induced damage to DNA, in Carcinogens Identification and Mechanisms of Action (A. C. Griffin and C. R. Shaw, eds.), pp. 229-250, Raven Press, New York. 

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