Disseminated intravascular clotting

Contraindications Evidence of active intravascular clotting process, disseminated intravascular coagulation without concurrent heparin therapy, hematuria of upper urinary tract origin (unless benefit outweighs risk) ... 

Plasma contains protease inhibitors that rapidly inactivate the coagulation proteins as they escape from the site of vessel injury. The most important proteins of this system are -anti protease, 2-macroglobulin, -antiplasmin, and antithrombin. If this system is overwhelmed, generalized intravascular clotting may occur. This process is called disseminated intravascular coagulation (DIC) and may follow massive tissue injury, cell lysis in malignant neoplastic disease, obstetric emergencies such as abruptio placentae, or bacterial sepsis. 

Deficiency of vitamin C due to a citrus-poor diet during pregnancy Hypervltaminosis A due to Ingestion of beef liver during pregnancy Deficiency of vitamin K because infant Intestines are sterile Deficiency of vitamin K because of disseminated Intravascular coagulation (disseminated clotting due to Infantile sepsis)... 

Heparin use in patients with disseminated intravascular coagulation may prevent the formation of new blood clots. The most common complication of heparin therapy is bleeding, so some clinicians find it too risky to justify its use. 

Thrombosis/embolism, diagnosis and treatment of disseminated intravascular coagulation (DIG), prophylaxis of deep vein thrombosis (DVT), clotting prevention Gearing intermittent infusion lines (heparin lock) to prevent clot formation at site... 

Disseminated intravascular coagulation (DIG) is another hemostasis disorder. It is a complex disorder that involves the development of small clots within the blood vessels and the dissolution of these clots. Platelets and the clotting factors often are consumed during this disease process, and intensive therapy is necessary to resolve its occurrence. 

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