Dipicolinates

Macrocyclic amides and esters containing the 2,6-dipicolinate subunit. . 241... 

Table 5.11. Macrocyclic esters containing the 3,5-dipicolinate subunit...

COCH Fig. 1.10 Pyridine 2,6-dicarbo lic acid, dipicolinic acid (DPA). 

Amador JA, BF Taylor (1990) Coupled metabolic and photolytic pathway for degradation of pyridinedicarbox-ylic acids, especially dipicolinic acid. Appl Environ Microbiol 56 1352-1356. 

Goodacre, R. Shann, B. Gilbert, R. J. Timmis, E. M. McGovern, A. C. Alsberg, B. K. Kell, D. B. Logan, N. A. Detection of the dipicolinic acid biomarker in Bacillus spores using Curie-point pyrolysis mass spectrometry and fourier transform infrared spectroscopy Anal. Chem. 2000,72,119-127. 

With the exception of some constituents such as high concentrations of calcium, dipicolinic aci d, and in Bacillus sphaericus, a, E-diaminopimelic acid, spore are similar to the vegetative cells in composition. 

Lamture, J.B., and Wensel, T.G. (1995) Intensely luminescent immunoreactive conjugates of proteins and dipicolinate-based polymeric Tb (III) chelates. Bioconjug Chem 6(1), 88-92. 

Diphenylphosphorochloridate, d748 1,3-Diphenyl-1,3-propanedione, d68 sym -Diphenylthiourea, 1141 Dipicolinic acid, p270 Di-2-propenylamine, d30... 

Reactions of [Pt(dipic)Cl] , dipic = dipicolinate, with 1-methylimida-zole or with 1,2-diaminoethane, monitored in DMF solution, involve replacement of chloride followed by opening of the dipic chelate ring (216). Kinetic data for acid-catalyzed ring opening in hydrolysis of [Pt(dipic)Cl] and of [Pt(glygly)Cl] (217) are compared with those for carboplatin (218) in Table VIII. 

It should be emphasized that, because small molecules in usual solvents have diffusion coefficients <10 cm2 s-1, the rapid diffusion limit can be attained only for donors with lifetimes of 1 ms. This is the case for lanthanide ions for instance, the lifetime of Tb3+ chelated to dipicolinate is 2.2 ms. Stryer and coworkers (1978) showed that using Tb3+ as a donor and rhodamine B as an acceptor, the concentration of rhodamine B resulting in 50% transfer was 6.7 x 10 6 M, which is three orders of magnitude less than the concentration corresponding to 50% transfer in the static limit. 

A Novel Fluorescent Sensing Technique for Dipicolinic acid... 

The peroxyacids were until relatively recently the most powerful oxidants of all organic peroxides, and it is often unnecessary to isolate them from the mixture of carboxylic acid and hydrogen peroxide used to generate them. The pine lower aliphatic members are explosive (performic, particularly) at high, but not low concentrations, being sensitive to heat but not usually to shock. Dipicolinic acid or phosphates have been used to stabilise these solutions. The detonable limits of peroxyacid solutions can be plotted by extrapolation from known data. Aromatic peroxyacids are generally more stable, particularly if ring substituents are present [1],... 

Table 20. Crystal parameters and bond distances in lanthanide dipicolinates 204—206)...

RuCl(en)(DPA), RuCl(bpy)(DPA) and RuCl(phen)(DPA) (DPA=2,6-dipicolinic acid) are made by reaction of RUCI3, the diamine and DPA in ethanol under reflux. The IR spectra and magnetic moments (p. 1.84, 1.79 and 1.78 B.M. respectively) were measured. As RuCl(bpy)(DPA) and RuCl(phen)(DPA)/PhlO or TBHP/water-dioxane they epoxidised styrene and norbomene and oxidised cyclohexane to cyclohexanol and cyclohexanone. A Ru (0)Cl(diamine)(DPA) species may be involved [792]. 

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